» Articles » PMID: 12939437

Interrupted Therapy: Stopping and Switching of the Beta-interferons Prescribed for MS

Overview
Journal Neurology
Specialty Neurology
Date 2003 Aug 27
PMID 12939437
Citations 74
Authors
Affiliations
Soon will be listed here.
Abstract

A retrospective chart review of patients in British Columbia with multiple sclerosis prescribed beta-interferon (IFNbeta) between 1995 and 2001 was carried out to investigate reasons for the interruption of therapy. The highest proportion of interruptions (76/281; 27%) occurred in the first 6 months. The single most common reason was perceived lack of efficacy, cited by 84 of 281 (30%). Gender, disability, and disease duration were identified as factors influencing interruption of IFNbeta therapy.

Citing Articles

Multiple sclerosis: time for early treatment with high-efficacy drugs.

Selmaj K, Cree B, Barnett M, Thompson A, Hartung H J Neurol. 2023; 271(1):105-115.

PMID: 37851189 PMC: 10769939. DOI: 10.1007/s00415-023-11969-8.


Comparison of dimethyl fumarate and interferon outcomes in an MS cohort.

Sattarnezhad N, Healy B, Baharnoori M, Diaz-Cruz C, Stankiewicz J, Weiner H BMC Neurol. 2022; 22(1):252.

PMID: 35820822 PMC: 9277810. DOI: 10.1186/s12883-022-02761-8.


Knowledge Is Power, but Is Ignorance Bliss? Optimising Conversations About Disease Progression in Multiple Sclerosis.

Vermersch P, Shanahan J, Langdon D, Yeandle D, Alexandri N, Schippling S Neurol Ther. 2019; 9(1):1-10.

PMID: 31748873 PMC: 7229099. DOI: 10.1007/s40120-019-00170-7.


A Novel Tool to Improve Shared Decision Making and Adherence in Multiple Sclerosis: Development and Preliminary Testing.

Col N, Alvarez E, Springmann V, Ionete C, Morales I, Solomon A MDM Policy Pract. 2019; 4(2):2381468319879134.

PMID: 31667351 PMC: 6798166. DOI: 10.1177/2381468319879134.


BG-12 and its potential for the prevention of relapse in multiple sclerosis.

Giannetti P, Niccolini F, Nicholas R Degener Neurol Neuromuscul Dis. 2019; 2:119-132.

PMID: 30890883 PMC: 6065565. DOI: 10.2147/DNND.S35790.