Selective Deficiency of Naïve CD4+ T-lymphocytes in a Child with Congenital Lymphoedema
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Abstract
We describe the first known case of congenital lymphoedema associated with selective deficit of naïve CD4+ T-lymphocytes. A high proportion of naïve CD4+ T-lymphocytes was found in the ascitic fluid, supporting the hypothesis of extra-vascular sequestration of these cells into lymphoedematous tissue.
Citing Articles
Pearce J, Hadcocks L, Mansour S, van Zanten M, Jeffery S, Gordon K Front Immunol. 2023; 14:1279077.
PMID: 38022535 PMC: 10656747. DOI: 10.3389/fimmu.2023.1279077.
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