[The FMRI Study of the Calculation Tasks in Normal Aged Volunteers]
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Objective: To investigate the feasibility and cortex activation of fMRI in aged volunteers during the performance of calculation tasks.
Methods: Internal mental calculation tasks including simple tasks and complicated tasks were conducted in 11 normal aged volunteers. The fMRI data was postprocessed using SPM99 to reveal the activated cortex.
Results: The simple calculation tasks were fulfilled satisfactorily in all aged subjects. Cortex in the bilateral Superior parietal lobule, inferior parietal lobule and bilateral occipital lobes showed activation. We found a selective enhancement of fMRI signal in Brodmann regions 9, 10 and 46 in the complicated tasks.
Conclusion: fMRI tasks are feasible in aged people and more cortex of the left frontal lobe shows activation in complicated calculation tasks.
Jiang Z, Zheng L J Zhejiang Univ Sci B. 2006; 7(5):357-64.
PMID: 16615165 PMC: 1462929. DOI: 10.1631/jzus.2006.B0357.
Jiang Z J Zhejiang Univ Sci B. 2005; 6(12):1213-9.
PMID: 16358382 PMC: 1390647. DOI: 10.1631/jzus.2005.B1213.