Treatment of Meningococcal Infection

Overview

Journal Arch Dis Child

Specialty Pediatrics

Date 2003 Jun 24

PMID 12818909

Citations 8

Authors

S B Welch

S Nadel

Affiliations

Soon will be listed here.

Abstract

Aggressive early treatment of meningococcal disease can reduce mortality. This relies on prompt recognition and treatment of the complications of septicaemia and meningitis, appropriate ongoing intensive care where necessary, and adequate management of multiple organ failure. Most children with meningococcal disease survive intact, but long term sequelae are increasingly recognised and make follow up essential. New treatments continue to be evaluated, but none has so far proven to be effective in further reducing morbidity or mortality. Simple, timely therapeutic manoeuvres may greatly improve the prospects for survival.

Citing Articles

Invasive Meningococcal Disease in the Vaccine Era.

Nadel S, Ninis N Front Pediatr. 2018; 6:321.

PMID: 30474022 PMC: 6237846. DOI: 10.3389/fped.2018.00321.

Mild meningococcaemia, pyrexia protocols and a problematic public health response.

Allen L BMJ Case Rep. 2014; 2014.

PMID: 24811106 PMC: 4025222. DOI: 10.1136/bcr-2013-203003.

Accuracy of the "traffic light" clinical decision rule for serious bacterial infections in young children with fever: a retrospective cohort study.

De S, Williams G, Hayen A, Macaskill P, McCaskill M, Isaacs D BMJ. 2013; 346:f866.

PMID: 23407730 PMC: 3571679. DOI: 10.1136/bmj.f866.

Invasive meningococcal infection: analysis of 110 cases from a tertiary care centre in North East India.

Hazarika R, Deka N, Khyriem A, Lyngdoh W, Barman H, Duwarah S Indian J Pediatr. 2012; 80(5):359-64.

PMID: 22821284 PMC: 7101621. DOI: 10.1007/s12098-012-0855-0.

Persistently low plasma thioredoxin is associated with meningococcal septic shock in children.

Callister M, Burke-Gaffney A, Quinlan G, Betts H, Nadel S, Evans T Intensive Care Med. 2006; 33(2):364-7.

PMID: 17115131 DOI: 10.1007/s00134-006-0460-7.

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