Gene Teams: a New Formalization of Gene Clusters for Comparative Genomics

Overview

Journal Comput Biol Chem

Publisher Elsevier

Date 2003 Jun 12

PMID 12798040

Citations 18

Authors

Nicolas Luc

Jean-Loup Risler

Anne Bergeron

Mathieu Raffinot

Affiliations

Soon will be listed here.

Abstract

This paper describes an efficient algorithm based on a new concept called gene team for detecting conserved gene clusters among an arbitrary number of chromosomes. Within the clusters, neither the order of the genes nor their orientation need be conserved. In addition, insertion of foreign genes within the clusters are permitted to a user-defined extent. This algorithm has been implemented in a publicly available TEAM software that proves to be an efficient tool for systematic searches of conserved gene clusters. Examples of actual biological results are provided. The software is downloadable from http://www-igm.univ-mlv.fr/ approximately raffinot/geneteam.html.

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