Post-shunt Resource Consumption Favors Small-diameter Prosthetic H-graft Portacaval Shunt over TIPS for Patients with Poor Hepatic Reserve
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Objective: To define the role of surgical shunting for patients with poor hepatic reserve (Child's class C) in the era of TIPS.
Summary Background Data: Most physicians prefer TIPS to surgical shunting for patients with poor hepatic reserve because of anticipated poor long-term survival.
Methods: Sixty-two patients of Child's class C with bleeding varices not amenable to endoscopic sclerotherapy or banding were prospectively randomized to undergo TIPS or 8-mm prosthetic H-graft portacaval shunt (HGPCS) from 1993 to 1999. Resource consumption and survival after shunting were determined.
Results: Twenty-nine patients underwent TIPS and 33 underwent HGPCS. After HGPCS, survival at 3 years was favorable but not statistically superior. TIPS was more often associated with shunt stenoses/occlusions, recurrent hemorrhage, shunt revisions, and shunt failure. Long-term follow-up documented that after HGPCS, patients required fewer hospital and ICU days and fewer units of RBCs transfused. After HGPCS, cost of care was less, as was the median cost of care per day of survival.
Conclusions: For Child's class C patients undergoing HGPCS or TIPS, long-term survival is similar, though favoring HGPCS. Similarly, measures of resource consumption and cost of care following hospital discharge favor HGPCS. HGPCS should be preferentially applied for acceptable patients without access to convenient capable post-shunt care or without definitive plans for imminent transplantation.
Roberts D, Best L, Freeman S, Sutton A, Cooper N, Arunan S Cochrane Database Syst Rev. 2021; 4:CD013155.
PMID: 33837526 PMC: 8094233. DOI: 10.1002/14651858.CD013155.pub2.
Torres M, Best L, Freeman S, Roberts D, Cooper N, Sutton A Cochrane Database Syst Rev. 2021; 3:CD013122.
PMID: 33784794 PMC: 8094621. DOI: 10.1002/14651858.CD013122.pub2.
Portosystemic shunt surgery in the era of TIPS: imaging-based planning of the surgical approach.
Fehrenbach U, Gul-Klein S, de Sousa Mendes M, Steffen I, Stern J, Geisel D Abdom Radiol (NY). 2020; 45(9):2726-2735.
PMID: 32504130 PMC: 8197708. DOI: 10.1007/s00261-020-02599-z.
Brand M, Prodehl L, Ede C Cochrane Database Syst Rev. 2018; 10:CD001023.
PMID: 30378107 PMC: 6516991. DOI: 10.1002/14651858.CD001023.pub3.
Extrahepatic portacaval shunt via a magnetic compression technique: A cadaveric feasibility study.
Yan X, Liu W, Ma J, Li J, Lv Y World J Gastroenterol. 2015; 21(26):8073-80.
PMID: 26185378 PMC: 4499349. DOI: 10.3748/wjg.v21.i26.8073.