Tandemly Repeated DNA Sequences and Centromeric Chromosomal Regions of Arabidopsis Species

Overview

Journal Chromosome Res

Date 2003 May 29

PMID 12769291

Citations 30

Authors

J S Heslop-Harrison

Andrea Brandes

Trude Schwarzacher

Affiliations

Soon will be listed here.

Abstract

Despite their common function, centromeric DNA sequences are not conserved between organisms. Most centromeres of animals and plants so far investigated have now been shown to consist of large blocks of tandemly repeated satellite sequences that are embedded in recombination-deficient heterochromatic regions. This central domain of satellite sequences that is postulated to mediate spindle attachment is surrounded by pericentromeric sequences incorporating various classes of repetitive sequences often including retroelements. The centromeric satellite DNA sequences are amongst the most rapidly evolving sequences and pose some fundamental problems of maintaining function. In this overview, we will discuss work on centromeric repetitive sequences in Arabidopsis thaliana and its relatives, and highlight some of the common features that are emerging when analysing closely related species.

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References

Kamm A, Schmidt T, Heslop-Harrison J . Molecular and physical organization of highly repetitive, undermethylated DNA from Pennisetum glaucum. Mol Gen Genet. 1994; 244(4):420-5. DOI: 10.1007/BF00286694. View

Chaves R, Guedes-Pinto H . Centromeric heterochromatin in the cattle rob(1;29) translocation: alpha-satellite I sequences, in-situ MspI digestion patterns, chromomycin staining and C-bands. Chromosome Res. 2000; 8(7):621-6. DOI: 10.1023/a:1009290125305. View

Kishii M, Nagaki K, Tsujimoto H . A tandem repetitive sequence located in the centromeric region of common wheat (Triticum aestivum) chromosomes. Chromosome Res. 2001; 9(5):417-28. DOI: 10.1023/a:1016739719421. View

Iwabuchi M, Itoh K, Shimamoto K . Molecular and cytological characterization of repetitive DNA sequences in Brassica. Theor Appl Genet. 2013; 81(3):349-55. DOI: 10.1007/BF00228675. View

Brandes A, Heslop-Harrison J, Kamm A, Kubis S, Doudrick R, Schmidt T . Comparative analysis of the chromosomal and genomic organization of Ty1-copia-like retrotransposons in pteridophytes, gymnosperms and angiosperms. Plant Mol Biol. 1997; 33(1):11-21. DOI: 10.1023/a:1005797222148. View

Clarke L, Amstutz H, Fishel B, Carbon J . Analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe. Proc Natl Acad Sci U S A. 1986; 83(21):8253-7. PMC: 386906. DOI: 10.1073/pnas.83.21.8253. View

Clarke L . Centromeres of budding and fission yeasts. Trends Genet. 1990; 6(5):150-4. DOI: 10.1016/0168-9525(90)90149-z. View

Huxley C . Mammalian artificial chromosomes and chromosome transgenics. Trends Genet. 1997; 13(9):345-7. DOI: 10.1016/s0168-9525(97)01256-0. View

Copenhaver G, Nickel K, Kuromori T, Benito M, Kaul S, Lin X . Genetic definition and sequence analysis of Arabidopsis centromeres. Science. 2000; 286(5449):2468-74. DOI: 10.1126/science.286.5449.2468. View

10.

Wolffe A, Pruss D . Deviant nucleosomes: the functional specialization of chromatin. Trends Genet. 1996; 12(2):58-62. DOI: 10.1016/0168-9525(96)81401-6. View

11.

Haupt W, Fischer T, Winderl S, Fransz P . The centromere1 (CEN1) region of Arabidopsis thaliana: architecture and functional impact of chromatin. Plant J. 2001; 27(4):285-96. DOI: 10.1046/j.1365-313x.2001.01087.x. View

12.

SMIT A, Riggs A . Tiggers and DNA transposon fossils in the human genome. Proc Natl Acad Sci U S A. 1996; 93(4):1443-8. PMC: 39958. DOI: 10.1073/pnas.93.4.1443. View

13.

Pelissier T, Tutois S, Tourmente S, Deragon J, Picard G . DNA regions flanking the major Arabidopsis thaliana satellite are principally enriched in Athila retroelement sequences. Genetica. 1996; 97(2):141-51. DOI: 10.1007/BF00054621. View

14.

Copenhaver G, Preuss D . Centromeres in the genomic era: unraveling paradoxes. Curr Opin Plant Biol. 1999; 2(2):104-8. DOI: 10.1016/S1369-5266(99)80021-1. View

15.

HARRISON G, Heslop-Harrison J . Centromeric repetitive DNA sequences in the genus Brassica. Theor Appl Genet. 2013; 90(2):157-65. DOI: 10.1007/BF00222197. View

16.

Hudakova S, Michalek W, Presting G, Ten Hoopen R, Dos Santos K, Jasencakova Z . Sequence organization of barley centromeres. Nucleic Acids Res. 2002; 29(24):5029-35. PMC: 97617. DOI: 10.1093/nar/29.24.5029. View

17.

Murata M, Ogura Y, Motoyoshi F . Centromeric repetitive sequences in Arabidopsis thaliana. Jpn J Genet. 1994; 69(4):361-70. DOI: 10.1266/jjg.69.361. View

18.

Gindullis F, Desel C, Galasso I, Schmidt T . The large-scale organization of the centromeric region in Beta species. Genome Res. 2001; 11(2):253-65. PMC: 311043. DOI: 10.1101/gr.162301. View

19.

Schmidt T, Heslop-Harrison J . High-resolution mapping of repetitive DNA by in situ hybridization: molecular and chromosomal features of prominent dispersed and discretely localized DNA families from the wild beet species Beta procumbens. Plant Mol Biol. 1996; 30(6):1099-113. DOI: 10.1007/BF00019545. View

20.

Singer M . Highly repeated sequences in mammalian genomes. Int Rev Cytol. 1982; 76:67-112. DOI: 10.1016/s0074-7696(08)61789-1. View