Vasoactive Intestinal Polypeptide: Abundant Immunoreactivity in Neural Cell Lines and Normal Nervous Tissue

Overview

Journal Science

Specialty Science

Date 1976 May 28

PMID 1273576

Citations 85

Authors

S I Said

R N Rosenberg

Affiliations

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Abstract

Vasoactive intestinal polypeptide immunoreactivity is present in high concentrations in clonal lines of neuronal and glial origin. The central nervous system and sympathetic ganglia are also rich in the peptide. The findings suggest that this peptide, hitherto thought limited to the gastrointestinal tract, is widely distributed in neural tissue and may have broad physiological significance.

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