Toward a Better Understanding of the Comparatively High Prostate Cancer Incidence Rates in Utah

Overview

Journal BMC Cancer

Publisher Biomed Central

Specialty Oncology

Date 2003 May 2

PMID 12720571

Citations 4

Authors

Ray M Merrill

Sterling C Hilton

Charles L Wiggins

Jared D Sturgeon

Affiliations

Soon will be listed here.

Abstract

Background: This study assesses whether comparatively high prostate cancer incidence rates among white men in Utah represent higher rates among members of the Church of Jesus Christ of Latter-day Saints (LDS or Mormons), who comprise about 70% of the state's male population, and considers the potential influence screening has on these rates.

Methods: Analyses are based on 14,693 histologically confirmed invasive prostate cancer cases among men aged 50 years and older identified through the Utah Cancer Registry between 1985 and 1999. Cancer records were linked to LDS Church membership records to determine LDS status. Poisson regression was used to derive rate ratios of LDS to nonLDS prostate cancer incidence, adjusted for age, disease stage, calendar time, and incidental detection.

Results: LDS men had a 31% (95% confidence interval, 26%-36%) higher incidence rate of prostate cancer than nonLDS men during the study period. Rates were consistently higher among LDS men over time (118% in 1985-88, 20% in 1989-92, 15% in 1993-1996, and 13% in 1997-99); age (13% in ages 50-59, 48% in ages 60-69, 28% in ages 70-79, and 16% in ages 80 and older); and stage (36% in local/regional and 17% in unstaged). An age- and stage-shift was observed for both LDS and nonLDS men, although more pronounced among LDS men.

Conclusions: Comparatively high prostate cancer incidence rates among LDS men in Utah are explained, at least in part, by more aggressive screening among these men.

Citing Articles

Latent Archetypes of the Spatial Patterns of Cancer.

Menezes T, Prates M, Assuncao R, De Castro M Stat Med. 2024; 43(27):5115-5137.

PMID: 39362794 PMC: 11583956. DOI: 10.1002/sim.10232.

Health Impacts of Religious Practices and Beliefs Associated with The Church of Jesus Christ of Latter-Day Saints.

de Diego Cordero R, Romero B J Relig Health. 2017; 56(4):1371-1380.

PMID: 28070765 DOI: 10.1007/s10943-016-0348-y.

Cancer screening practices among Amish and non-Amish adults living in Ohio Appalachia.

Katz M, Ferketich A, Paskett E, Harley A, Reiter P, Lemeshow S J Rural Health. 2011; 27(3):302-9.

PMID: 21729158 PMC: 3130935. DOI: 10.1111/j.1748-0361.2010.00345.x.

Family history of prostate and breast cancer and the risk of prostate cancer in the PSA era.

Chen Y, Page J, Chen R, Giovannucci E Prostate. 2008; 68(14):1582-91.

PMID: 18646000 PMC: 2574825. DOI: 10.1002/pros.20825.

References

Merrill R, Thygerson A . Religious preference, church activity, and physical exercise. Prev Med. 2001; 33(1):38-45. DOI: 10.1006/pmed.2001.0851. View

Merrill R, Feuer E, Warren J, Schussler N, Stephenson R . Role of transurethral resection of the prostate in population-based prostate cancer incidence rates. Am J Epidemiol. 1999; 150(8):848-60. DOI: 10.1093/oxfordjournals.aje.a010090. View

Merrill R . Demographics and health-related factors of men receiving prostate-specific antigen screening in Utah. Prev Med. 2001; 33(6):646-52. DOI: 10.1006/pmed.2001.0940. View

Mandel J, SCHUMAN L . Sexual factors and prostatic cancer: results from a case-control study. J Gerontol. 1987; 42(3):259-64. DOI: 10.1093/geronj/42.3.259. View

Catalona W, Bigg S . Nerve-sparing radical prostatectomy: evaluation of results after 250 patients. J Urol. 1990; 143(3):538-43; discussion 544. DOI: 10.1016/s0022-5347(17)40013-9. View

Friedman G, Hiatt R, Quesenberry Jr C, Selby J . Case-control study of screening for prostatic cancer by digital rectal examinations. Lancet. 1991; 337(8756):1526-9. DOI: 10.1016/0140-6736(91)93207-p. View

Wajda A, Roos L, Layefsky M, Singleton J . Record linkage strategies: Part II. Portable software and deterministic matching. Methods Inf Med. 1991; 30(3):210-4. View

Labrie F, Dupont A, Suburu R, Cusan L, Tremblay M, Gomez J . Serum prostate specific antigen as pre-screening test for prostate cancer. J Urol. 1992; 147(3 Pt 2):846-51; discussion 851-2. DOI: 10.1016/s0022-5347(17)37402-5. View

Gerber G, Thompson I, Thisted R, Chodak G . Disease-specific survival following routine prostate cancer screening by digital rectal examination. JAMA. 1993; 269(1):61-4. View

10.

Catalona W, Smith D, Ratliff T, Basler J . Detection of organ-confined prostate cancer is increased through prostate-specific antigen-based screening. JAMA. 1993; 270(8):948-54. View

11.

La Vecchia C, Franceschi S, Talamini R, Negri E, Boyle P, DAvanzo B . Marital status, indicators of sexual activity and prostatic cancer. J Epidemiol Community Health. 1993; 47(6):450-3. PMC: 1059857. DOI: 10.1136/jech.47.6.450. View

12.

Lyon J, Gardner K, Gress R . Cancer incidence among Mormons and non-Mormons in Utah (United States) 1971-85. Cancer Causes Control. 1994; 5(2):149-56. DOI: 10.1007/BF01830261. View

13.

Mills P, Beeson W, Phillips R, Fraser G . Cancer incidence among California Seventh-Day Adventists, 1976-1982. Am J Clin Nutr. 1994; 59(5 Suppl):1136S-1142S. DOI: 10.1093/ajcn/59.5.1136S. View

14.

Potosky A, Miller B, Albertsen P, Kramer B . The role of increasing detection in the rising incidence of prostate cancer. JAMA. 1995; 273(7):548-52. View

15.

Waterbor J, Bueschen A . Prostate cancer screening (United States). Cancer Causes Control. 1995; 6(3):267-74. DOI: 10.1007/BF00051798. View

16.

Krongrad A, Lai H, Burke M, Goodkin K, Lai S . Marriage and mortality in prostate cancer. J Urol. 1996; 156(5):1696-70. View

17.

Merrill R, Potosky A, Feuer E . Changing trends in U.S. prostate cancer incidence rates. J Natl Cancer Inst. 1996; 88(22):1683-5. DOI: 10.1093/jnci/88.22.1683. View

18.

Hofer T, Katz S . Healthy behaviors among women in the United States and Ontario: the effect on use of preventive care. Am J Public Health. 1996; 86(12):1755-9. PMC: 1380729. DOI: 10.2105/ajph.86.12.1755. View

19.

. Screening for prostate cancer. American College of Physicians. Ann Intern Med. 1997; 126(6):480-4. View

20.

Merrill R, Brawley O . Prostate cancer incidence and mortality rates among white and black men. Epidemiology. 1997; 8(2):126-31. DOI: 10.1097/00001648-199703000-00001. View