Alpha 2.0
Login Register
» Articles » PMID: 1269987

Cell Mediated Immunity to Corn Starch in Starch-induced Granulomatous Peritonitis

Overview
Journal Gut
Specialty Gastroenterology
Date 1976 Mar 1
PMID 1269987
Citations 4
Authors
R L Goodacre
R L Clancy
R A Davidson
J E MULLENS
Affiliations
Soon will be listed here.
Abstract

Two patients with histologically diagnosed starch induced granulomatous peritonitis (SGP) have been shown to have cell mediated immunity to corn starch using the techniques of macrophage migration inhibition and lymphocyte DNA synthesis. Control groups of normal subjects, patients with uncomplicated laparotomy, and patients with Crohn's disease were negative in both tests. Lymphocytes from two patients with band adhesions, one of whom had biopsy evidence of a granulomatous reaction to starch, were sensitized to starch. Cell mediated immunity to starch may contribute to the pathogenesis of SGP, and some band adhesions may be a chronic low grade manifestation of this disorder.

Citing Articles

Diagnostic Value of Oral Provocation Tests in Drug Hypersensitivity Reactions Induced by Nonsteroidal Anti-Inflammatory Drugs and Paracetamol.

Popiolek I, Blasiak M, Kozak A, Pietak E, Bulanda M, Porebski G Diagnostics (Basel). 2022; 12(12).

PMID: 36553081 PMC: 9777020. DOI: 10.3390/diagnostics12123074.

In vitro toxicity determination of antifungal constituents from Combretum zeyheri.

Mapfunde S, Sithole S, Mukanganyama S BMC Complement Altern Med. 2016; 16:162.

PMID: 27251466 PMC: 4890497. DOI: 10.1186/s12906-016-1150-9.

Pharmaceutical excipients. Adverse effects associated with 'inactive' ingredients in drug products (Part II).

Golightly L, Smolinske S, Bennett M, Sutherland 3rd E, Rumack B Med Toxicol Adverse Drug Exp. 1988; 3(3):209-40.

PMID: 3041246 DOI: 10.1007/BF03259883.

Granulomatous peritonitis and appendicitis of food starch origin.

Veress B, Alafuzoff I, Juliusson G Gut. 1991; 32(6):718-20.

PMID: 2060884 PMC: 1378898. DOI: 10.1136/gut.32.6.718.

References
1.
David J . Lymphocyte mediators and cellular hypersensitivity. N Engl J Med. 1973; 288(3):143-9. DOI: 10.1056/NEJM197301182880311. View
2.
Marsman A, van der Hart M, WALIG C, EIJSVOOGEL V . Migration inhibition experiments with mixtures of human peripheral blood lymphocytes and guinea pig peritoneal exudate cells. Eur J Immunol. 1972; 2(6):546-50. DOI: 10.1002/eji.1830020614. View
3.
SODERBERG Jr C, Lou T, RANDALL H . Glove starch granulomatous peritonitis. Am J Surg. 1973; 125(4):455-60. DOI: 10.1016/0002-9610(73)90081-0. View
4.
MYERS R, DEAVER J, Brown C . Granulomatous peritonitis due to starch glove powder: a clinical and experimental study. Ann Surg. 1960; 151:106-12. PMC: 1613352. View
5.
Clancy R, Bienenstock J . The proliferative response of bronchus-associated lymphoid tissue after local and systemic immunization. J Immunol. 1974; 112(6):1997-2001. View