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An Eight-cysteine-containing CFEM Domain Unique to a Group of Fungal Membrane Proteins

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Specialty Biochemistry
Date 2003 Mar 14
PMID 12633989
Citations 135
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Abstract

CFEM, an eight cysteine-containing domain, has been identified by analyzing over 25 fungal sequences selected from database sequence searches. Features of CFEM suggest that it is a novel domain with characteristics distinct from known cysteine-rich domains. Some CFEM-containing proteins (e.g. Pth11 from Magnaporthe grisea) are proposed to have important roles in fungal pathogenesis.

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