Gliding Motility: the Molecules Behind the Motion

Overview

Journal Curr Biol

Publisher Cell Press

Specialty Biology

Date 2003 Jan 28

PMID 12546805

Citations 5

Authors

Matthew B Heintzelman

Affiliations

Soon will be listed here.

Abstract

In apicomplexan parasites, gliding motility and host cell invasion are driven by an actomyosin-based system. Recent studies have characterized several components of the gliding motility apparatus and have provided new insight into the molecular architecture of this locomotory system.

Citing Articles

Defining the morphology and mechanism of the hemoglobin transport pathway in Plasmodium falciparum-infected erythrocytes.

Milani K, Schneider T, Taraschi T Eukaryot Cell. 2015; 14(4):415-26.

PMID: 25724884 PMC: 4385801. DOI: 10.1128/EC.00267-14.

IMC1b is a putative membrane skeleton protein involved in cell shape, mechanical strength, motility, and infectivity of malaria ookinetes.

Tremp A, Khater E, Dessens J J Biol Chem. 2008; 283(41):27604-27611.

PMID: 18650444 PMC: 2562075. DOI: 10.1074/jbc.M801302200.

Developmental biology of sporozoite-host interactions in Plasmodium falciparum malaria: implications for vaccine design.

Garcia J, Puentes A, Patarroyo M Clin Microbiol Rev. 2006; 19(4):686-707.

PMID: 17041140 PMC: 1592691. DOI: 10.1128/CMR.00063-05.

Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor.

Bosch J, Turley S, Daly T, Bogh S, Villasmil M, Roach C Proc Natl Acad Sci U S A. 2006; 103(13):4852-7.

PMID: 16547135 PMC: 1458759. DOI: 10.1073/pnas.0510907103.

A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii.

Carey K, Westwood N, Mitchison T, Ward G Proc Natl Acad Sci U S A. 2004; 101(19):7433-8.

PMID: 15123807 PMC: 409936. DOI: 10.1073/pnas.0307769101.