Termination of Translation: Interplay of MRNA, RRNAs and Release Factors?

Overview

Journal EMBO J

Specialties Biotechnology
Molecular Biology

Date 2003 Jan 7

PMID 12514123

Citations 80

Authors

Lev Kisselev

Mans Ehrenberg

Ludmila Frolova

Affiliations

Soon will be listed here.

Abstract

Termination of translation in eukaryotes has focused recently on functional anatomy of polypeptide chain release factor, eRF1, by using a variety of different approaches. The tight correlation between the domain structure and different functions of eRF1 has been revealed. Independently, the role of prokaryotic RF1/2 in GTPase activity of RF3 has been deciphered, as well as RF3 function itself.

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