Hypopharyngeal PH Monitoring Artifact in Detection of Laryngopharyngeal Reflux

Overview

Journal Dig Dis Sci

Specialty Gastroenterology

Date 2002 Nov 28

PMID 12452398

Citations 5

Authors

John M Wo

Abdul Jabbar

Welby Winstead

Steve Goudy

Robert Cacchione

Jeff W Allen

Affiliations

Soon will be listed here.

Abstract

Hypopharyngeal pH artifacts have been a concern in the detection of laryngopharyngeal reflux. Our purpose was to analyze and quantify artifacts from dual-sensor hypopharyngeal pH monitoring. In all, 42 hypopharyngeal and 58 esophageal pH studies were reviewed. Type 1 (out of range), type 2 (pH drift), and type 3 (isolated pH drop) artifacts were identified. The proportion of proximal-sensor pH drop to <4 that was artifactual was determined. The median number (range) of artifacts was 1 (0-17) and 2 (0-28) for hypopharyngeal and esophageal pH studies, respectively (P = NS). The median proportion of artifactual pH drop to <4 was 1% (0-84%) and 2% (0-74%) for hypopharyngeal and esophageal pH studies, respectively (P = NS). The diagnosis did not change in any patient after excluding pH artifacts. In all, 19% of the combined 2,432 hypopharyngeal pH drops of <4 were artifacts. In conclusion, hypopharyngeal pH artifacts per study were uncommon but can be prominent in a few patients. One can identify these artifacts and exclude them from analysis.

Citing Articles

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duricek M, Banovcin P, Halickova T, Hyrdel R, Kollarik M Dig Dis Sci. 2018; 64(5):1270-1280.

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A Study to Draw a Normative Database of Laryngopharynx pH Profile in Chinese.

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Ratio between proximal/distal gastroesophageal reflux does not discriminate abnormal proximal reflux.

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A new technique for measurement of pharyngeal pH: normal values and discriminating pH threshold.

Ayazi S, Lipham J, Hagen J, Tang A, Zehetner J, Leers J J Gastrointest Surg. 2009; 13(8):1422-9.

PMID: 19421822 DOI: 10.1007/s11605-009-0915-6.

Proximal sensor data from routine dual-sensor esophageal pH monitoring is often inaccurate.

McCollough M, Jabbar A, Cacchione R, Allen J, Harrell S, Wo J Dig Dis Sci. 2004; 49(10):1607-11.

PMID: 15573913 DOI: 10.1023/b:ddas.0000043372.98660.82.

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