Efficient Interstrand Excess Electron Transfer in PNA:DNA Hybrids

Overview

Journal J Am Chem Soc

Publisher American Chemical Society

Specialty Chemistry

Date 2002 Nov 21

PMID 12440883

Citations 4

Authors

Michaela K Cichon

Clemens H Haas

Friederike Grolle

Alexandra Mees

Thomas Carell

Affiliations

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Abstract

PNA:DNA strands were prepared containing a flavin electron donor and a thymine dimer acceptor, which gives a strand break upon single electron reduction. With these constructs, it was confirmed that an excess electron transfer through the base stack can be efficient in an interstrand fashion. The effect of an increased distance, a changed sequence, and stacking was explored.

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