Functional Heartburn: the Stimulus, the Pain, and the Brain

Overview

Journal Gut

Specialty Gastroenterology

Date 2002 Nov 13

PMID 12427796

Citations 60

Authors

R Fass

G Tougas

Affiliations

Soon will be listed here.

Abstract

Functional heartburn is a common disorder and appears to be composed of several distinct subgroups. Identifying the different subgroups based on clinical history only is not achievable at present. The mechanisms responsible for pain, clinical characteristics, and the optimal therapeutic approach remain poorly understood. Response to potent antireflux treatment is relatively limited. Current and future treatment strategies for functional heartburn patients who have failed standard dose proton pump inhibitors (PPIs) include increased PPI dose in some, as well as addition of pain modulators in others.

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