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Current Options for the Treatment of Neoplastic Meningitis

Overview
Journal J Neurooncol
Publisher Springer
Date 2002 Nov 6
PMID 12416549
Citations 6
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Abstract

Neoplastic meningitis, which is the diffuse involvement of the leptomeninges by infiltrating cancer cells, may be caused by many systemic tumors. The treatment options for neoplastic meningitis disease remain unsatisfactory. In this review article, we discuss the pathogenesis and cytology of neoplastic meningitis and the options for treatment, including intrathecal chemotherapy, systemic chemotherapy, and newer agents such as cytokines and monoclonal antibodies.

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