Neuroprotective and Neurorestorative Strategies for Parkinson's Disease

Overview

Journal Nat Neurosci

Date 2002 Oct 31

PMID 12403986

Citations 47

Authors

Ted M Dawson

Valina L Dawson

Affiliations

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Abstract

Advances in understanding the molecular mechanisms of cell death and the pathogenesis of sporadic and familial Parkinson's disease are creating new opportunities for the development of neuroprotective and/or neurorestorative therapies. Here we review many of these advances, highlighting areas and strategies that might be particularly suited to the development of innovative approaches that prevent degeneration and/or restore function in Parkinson's disease.

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