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The Developing Synapse: Construction and Modulation of Synaptic Structures and Circuits

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Journal Science
Specialty Science
Date 2002 Oct 26
PMID 12399577
Citations 157
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Abstract

Synapse formation and stabilization in the vertebrate central nervous system is a dynamic process, requiring bi-directional communication between pre- and postsynaptic partners. Numerous mechanisms coordinate where and when synapses are made in the developing brain. This review discusses cellular and activity-dependent mechanisms that control the development of synaptic connectivity.

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