Bactericidal Effects of Fatty Acids and Monoglycerides on Helicobacter Pylori

Overview

Journal Int J Antimicrob Agents

Specialties Infectious Diseases
Pharmacology

Date 2002 Oct 19

PMID 12385681

Citations 34

Authors

Gudmundur Bergsson

Olafur Steingrimsson

Halldor Thormar

Affiliations

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Abstract

The susceptibility of Salmonella spp., Escherichia coli and Helicobacter pylori to fatty acids and monoglycerides was studied. None of the lipids showed significant antibacterial activity against Salmonella spp. and E. coli but eight of 12 lipids tested showed high activity against H. pylori, monocaprin and monolaurin being the most active. The high activity of monoglycerides against H. pylori suggests that they may be useful as active ingredients in pharmaceutical formulations.

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