» Articles » PMID: 12372749

Medulloblastoma with Extensive Nodularity: Single Photon Emission CT Study with Iodine-123 Metaiodobenzylguanidine

Overview
Specialty Neurology
Date 2002 Oct 10
PMID 12372749
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

We present the case of an infant with medulloblastoma with extensive nodularity, which had been called cerebellar neuroblastoma. MR imaging clearly revealed a nodular enhancement, which appeared as a grape-like lesion. Single photon emission CT revealed markedly high iodine-123 metaiodobenzylguanidine uptake in the enhancing tumor. Iodine-123 metaiodobenzylguanidine single photon emission CT may be useful in the diagnosis of medulloblastoma with extensive nodularity, which has been considered to be a subgroup of medulloblastoma with extensive neuronal differentiation.

Citing Articles

2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist.

McNamara C, Mankad K, Thust S, Dixon L, Limback-Stanic C, DArco F Neuroradiology. 2022; 64(10):1919-1950.

PMID: 35869291 DOI: 10.1007/s00234-022-03008-6.


MRI features as a helpful tool to predict the molecular subgroups of medulloblastoma: state of the art.

Colafati G, Voicu I, Carducci C, Miele E, Carai A, Di Loreto S Ther Adv Neurol Disord. 2018; 11:1756286418775375.

PMID: 29977341 PMC: 6024494. DOI: 10.1177/1756286418775375.


123I-metaiodobenzylguanidine single-photon emission computerized tomography in brain tumors - a preliminary study.

Sasajima T, Kinouchi H, Naitoh Y, Tomura N, Watarai J, Mizoi K J Neurooncol. 2005; 77(2):185-91.

PMID: 16314956 DOI: 10.1007/s11060-005-9021-0.

References
1.
Sasajima T, Kinouchi H, Tomura N, Watarai J, Mizoi K . Innovative approach in the diagnosis of medulloblastoma in which the 123I-metaiodobenzylguanidine single-photon emission computerized tomography technique is used. Case illustration. J Neurosurg. 2000; 93(1):145. DOI: 10.3171/jns.2000.93.1.0145. View

2.
Iavarone A, Lasorella A, Servidei T, Riccardi R, Mastrangelo R . Uptake and storage of m-iodobenzylguanidine are frequent neuronal functions of human neuroblastoma cell lines. Cancer Res. 1993; 53(2):304-9. View

3.
Sugita Y, Miyagi J, Yamamoto T, Morimoto K, Shigemori M, Morimatsu M . Neuroblastomas of the central nervous system--clinicopathological features of a cerebellar neuroblastoma in comparison with a metastatic cerebral neuroblastoma. Kurume Med J. 1994; 41(2):87-95. DOI: 10.2739/kurumemedj.41.87. View

4.
Clerc J, Halpern S, Fourre C, Omri F, Briancon C, Jeusset J . SIMS microscopy imaging of the intratumor biodistribution of metaiodobenzylguanidine in the human SK-N-SH neuroblastoma cell line xenografted into nude mice. J Nucl Med. 1993; 34(9):1565-70. View

5.
Robson J, Sidell N . Ultrastructural features of a human neuroblastoma cell line treated with retinoic acid. Neuroscience. 1985; 14(4):1149-62. DOI: 10.1016/0306-4522(85)90284-2. View