Medulloblastoma with Extensive Nodularity: Single Photon Emission CT Study with Iodine-123 Metaiodobenzylguanidine
Overview
Affiliations
We present the case of an infant with medulloblastoma with extensive nodularity, which had been called cerebellar neuroblastoma. MR imaging clearly revealed a nodular enhancement, which appeared as a grape-like lesion. Single photon emission CT revealed markedly high iodine-123 metaiodobenzylguanidine uptake in the enhancing tumor. Iodine-123 metaiodobenzylguanidine single photon emission CT may be useful in the diagnosis of medulloblastoma with extensive nodularity, which has been considered to be a subgroup of medulloblastoma with extensive neuronal differentiation.
2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist.
McNamara C, Mankad K, Thust S, Dixon L, Limback-Stanic C, DArco F Neuroradiology. 2022; 64(10):1919-1950.
PMID: 35869291 DOI: 10.1007/s00234-022-03008-6.
Colafati G, Voicu I, Carducci C, Miele E, Carai A, Di Loreto S Ther Adv Neurol Disord. 2018; 11:1756286418775375.
PMID: 29977341 PMC: 6024494. DOI: 10.1177/1756286418775375.
Sasajima T, Kinouchi H, Naitoh Y, Tomura N, Watarai J, Mizoi K J Neurooncol. 2005; 77(2):185-91.
PMID: 16314956 DOI: 10.1007/s11060-005-9021-0.