Free Radical Scavengers from the Heartwood of Juniperus Chinensis

Overview

Journal Arch Pharm Res

Specialty Pharmacology

Date 2002 Sep 7

PMID 12214854

Citations 3

Authors

Jong Pil Lim

Young Cheol Song

Jin Wook Kim

Chung Hwan Ku

Jae Soon Eun

Kang Hyun Leem

Dae Keun Kim

Affiliations

Soon will be listed here.

Abstract

The antioxidant activity of Juniperus chinensis (Cupressaceae) was determined by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl). The methanolic extract of J. chinensis heartwood showed the strong antioxidant activity. The antioxidant activity of n-BuOH soluble fraction was stronger than that of the others, and the fraction was subjected to purification by repeated silica gel and Sephadex LH-20 column chromatography. Quercetin, naringenin, taxifolin, aromadendrin and isoquercitrin were isolated from the n-BuOH fraction. Their structures were elucidated by physico-chemical and spectroscopic studies.

Citing Articles

Sephadex LH-20, Isolation, and Purification of Flavonoids from Plant Species: A Comprehensive Review.

Mottaghipisheh J, Iriti M Molecules. 2020; 25(18).

PMID: 32927822 PMC: 7570886. DOI: 10.3390/molecules25184146.

Radical-Scavenging Activity and Ferric Reducing Ability of Juniperus thurifera (L.), J. oxycedrus (L.), J. phoenicea (L.) and Tetraclinis articulata (L.).

El Jemli M, Kamal R, Marmouzi I, Zerrouki A, Cherrah Y, Alaoui K Adv Pharmacol Sci. 2016; 2016:6392656.

PMID: 27293428 PMC: 4884791. DOI: 10.1155/2016/6392656.

Antioxidant activity of leaves and fruits of Iranian conifers.

Emami S, Asili J, Mohagheghi Z, Hassanzadeh M Evid Based Complement Alternat Med. 2007; 4(3):313-9.

PMID: 17965761 PMC: 1978238. DOI: 10.1093/ecam/nem011.