[Effect of Ganoderma Polysaccharides on CAMP in Murine Peritoneal Macrophages]

Objective: Investigating the effect of GLB7 on cAMP in murine peritoneal macrophages to provide a scientific evidence for the immunomodulatory mechanism.

Method: Cell culture and radio-immunological assay of cAMP were used.

Result: GLB7 increased the production of cAMP in a concentration and time dependent manner in murine peritoneal macrophages.

Conclusion: The immunopotentiating effect of GLB7 may be due to the activation of macrophages that leads to the increase of cAMP.