Unilateral Retinal Vasculitis, Branch Retinal Artery Occlusion and Subsequent Retinal Neovascularization in Crohn's Disease

Overview

Journal Int Ophthalmol

Specialty Ophthalmology

Date 2002 Aug 31

PMID 12201349

Citations 10

Authors

O A Saatci

N Kocak

I Durak

M H Ergin

Affiliations

Soon will be listed here.

Abstract

Purpose: To report on a case of Crohn's disease and unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization.

Methods: We examined a 38-year-old woman with severe left visual loss and biopsy-proven Crohn's disease diagnosed four years prior to the ocular involvement. A Heidelberg scanning laser ophthalmoscope was used for fundus fluorescein angiography and indocyanine green angiography. Retinal neovascularization was detected during the follow-up.

Results: Successful regression of retinal neovascularization was achieved after argon green laser panretinal photocoagulation in addition to oral steroid and salazopyrine.

Conclusion: Retinal vascular involvement is a rare ocular feature of Crohn's disease and may result in retinal neovascularization that may necessitate prompt laser photocoagulation.

Citing Articles

Ocular extraintestinal manifestations and treatments in patients with inflammatory bowel disease.

Rodriguez Duran M, OKeefe G Front Ophthalmol (Lausanne). 2024; 3:1257068.

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Simultaneous central retinal artery occlusion and optic nerve vasculitis in Crohn disease.

Coussa R, Ali-Ridha A, Vila N, Alshareef R, Chen J Am J Ophthalmol Case Rep. 2018; 5:11-15.

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Ophthalmic manifestations in patients with inflammatory bowel disease: A review.

Troncoso L, Biancardi A, Moraes Jr H, Zaltman C World J Gastroenterol. 2017; 23(32):5836-5848.

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Risk of Retinal Neovascularization in Cases of Uveitis.

Patel A, Newcomb C, Liesegang T, Pujari S, Suhler E, Thorne J Ophthalmology. 2015; 123(3):646-54.

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Central retinal vein occlusion in a patient with retinal vasculitis and Crohn's disease.

Figueiredo L, Rothwell R, Brandao A, Fonseca S Case Rep Ophthalmol Med. 2014; 2014:967878.

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References

Macoul K . Ocular changes in granulomatous ileocolitis. Arch Ophthalmol. 1970; 84(1):95-7. DOI: 10.1001/archopht.1970.00990040097023. View

Soukiasian S, Foster C, Raizman M . Treatment strategies for scleritis and uveitis associated with inflammatory bowel disease. Am J Ophthalmol. 1994; 118(5):601-11. DOI: 10.1016/s0002-9394(14)76575-4. View

Duker J, Brown G, Brooks L . Retinal vasculitis in Crohn's disease. Am J Ophthalmol. 1987; 103(5):664-8. DOI: 10.1016/s0002-9394(14)74326-0. View

Garcia-Diaz M, Mira M, Nevado L, Galvan A, Berenguer A, Bureo J . Retinal vasculitis associated with Crohn's disease. Postgrad Med J. 1995; 71(833):170-2. PMC: 2398158. DOI: 10.1136/pgmj.71.833.170. View

Danzi J . Extraintestinal manifestations of idiopathic inflammatory bowel disease. Arch Intern Med. 1988; 148(2):297-302. View

Sedwick L, Klingele T, BURDE R, Behrens M . Optic neuritis in inflammatory bowel disease. J Clin Neuroophthalmol. 1984; 4(1):3-6. View

Schneiderman J, Sharpe J, Sutton D . Cerebral and retinal vascular complications of inflammatory bowel disease. Ann Neurol. 1979; 5(4):331-7. DOI: 10.1002/ana.410050405. View

Zegarra H, GUTMAN F, ZAKOV N, Carim M . Partial occlusion of the central retinal vein. Am J Ophthalmol. 1983; 96(3):330-7. DOI: 10.1016/s0002-9394(14)77824-9. View

PETRELLI E, McKinley M, Troncale F . Ocular manifestations of inflammatory bowel disease. Ann Ophthalmol. 1982; 14(4):356-60. View

10.

Salmon J, Wright J, Murray A . Ocular inflammation in Crohn's disease. Ophthalmology. 1991; 98(4):480-4. DOI: 10.1016/s0161-6420(91)32268-1. View

11.

Greenstein A, Janowitz H, Sachar D . The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients. Medicine (Baltimore). 1976; 55(5):401-12. DOI: 10.1097/00005792-197609000-00004. View

12.

Ruby A, Jampol L . Crohn's disease and retinal vascular disease. Am J Ophthalmol. 1990; 110(4):349-53. DOI: 10.1016/s0002-9394(14)77013-8. View

13.

Sykes S, Horton J . Steroid-responsive retinal vasculitis with a frosted branch appearance in Crohns disease. Retina. 1997; 17(5):451-4. DOI: 10.1097/00006982-199709000-00017. View

14.

Hopkins D, Horan E, Burton I, Clamp S, de Dombal F, Goligher J . Ocular disorders in a series of 332 patients with Crohn's disease. Br J Ophthalmol. 1974; 58(8):732-7. PMC: 1215010. DOI: 10.1136/bjo.58.8.732. View

15.

Ernst B, Lowder C, Meisler D, GUTMAN F . Posterior segment manifestations of inflammatory bowel disease. Ophthalmology. 1991; 98(8):1272-80. DOI: 10.1016/s0161-6420(91)32143-2. View