NADPH Oxidase(s): New Source(s) of Reactive Oxygen Species in the Vascular System?

Overview

Journal J Clin Pathol

Specialty Pathology

Date 2002 Jul 31

PMID 12147646

Citations 25

Authors

L van Heerebeek

C Meischl

W Stooker

C J L M Meijer

H W M Niessen

D Roos

Affiliations

Soon will be listed here.

Abstract

Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species. In the present review, we discuss the detection of the different components of NADP oxidase(s) in the vascular system, together with the putative role of reactive oxygen species produced by vascular NADPH oxidase(s), in both in vitro and in vivo studies.

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