Acetaminophen (paracetamol)-induced Anaphylactic Shock
Overview
General Surgery
Affiliations
Acetaminophen (paracetamol) is a widely prescribed analgesic-antipyretic drug. Adverse allergic reactions to this drug are rare. We report a case of anaphylactic shock due to acetaminophen. Results of skin prick tests and intradermal tests were negative. Oral rechallenge resulted in generalized urticaria associated with an increased plasma level of histamine. Acetaminophen should be added to the list of causes of anaphylaxis.
Rathjens L, Gwiasda M, Schwarz S, Mohler R, Martin D, Jenetzky E Children (Basel). 2023; 10(2).
PMID: 36832514 PMC: 9954832. DOI: 10.3390/children10020385.
Acetaminophen-induced anaphylaxis: a case report.
Sunwoo J, Kim H, Bae K Transl Clin Pharmacol. 2021; 29(2):88-91.
PMID: 34235121 PMC: 8255548. DOI: 10.12793/tcp.2021.29.e8.
Martin D, Wachtmeister J, Ludwigs K, Jenetzky E BMC Med Inform Decis Mak. 2020; 20(1):249.
PMID: 33004050 PMC: 7528253. DOI: 10.1186/s12911-020-01269-w.
Flare-Up Phenomenon of Intradermal Test with Anaphylactic Reaction to Paracetamol (Acetaminophen).
Rodriguez-Fernandez A, Sanchez-Dominguez M, Noguerado-Mellado B, Rojas-Perez-Ezquerra P Recent Pat Inflamm Allergy Drug Discov. 2018; 13(1):69-72.
PMID: 30255762 PMC: 6778981. DOI: 10.2174/1872213X12666180926115034.
Fever: Views in Anthroposophic Medicine and Their Scientific Validity.
Martin D Evid Based Complement Alternat Med. 2016; 2016:3642659.
PMID: 27999605 PMC: 5143743. DOI: 10.1155/2016/3642659.