Radiotherapy-induced Cerebral Abnormalities in Patients with Low-grade Glioma

Overview

Journal Neurology

Specialty Neurology

Date 2002 Jul 10

PMID 12105319

Citations 33

Authors

T J Postma

M Klein

C C P Verstappen

J E C Bromberg

M Swennen

J A Langendijk

M J B Taphoorn

P Scheltens

B J Slotman

H M VAN DER Ploeg

N K Aaronson

J J Heimans

Affiliations

Soon will be listed here.

Abstract

Abnormalities on CT or MRI and neuropsychological performance in patients with low-grade glioma, with (n = 23) or without (n = 16) prior cerebral radiotherapy, were evaluated. Cerebral atrophy was observed in 14 of 23 patients (61%) treated with prior radiotherapy, and in 1 of 16 patients (6%) without prior radiotherapy. White matter abnormalities were observed in six patients, all of whom were treated with prior radiotherapy. These radiologic cerebral abnormalities correlated with cognitive performance.

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