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Iroquois Genes: Genomic Organization and Function in Vertebrate Neural Development

Overview
Publisher Elsevier
Specialties Biology
Genetics
Date 2002 Jul 9
PMID 12100884
Citations 73
Authors
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Abstract

We review recent work that shows that the iroquois (Iro/Irx) homeobox genes have conserved genomic organization in Drosophila and vertebrates. In addition, these genes play pivotal functions in the initial specification of the vertebrate neuroectoderm, and, in collaboration with other transcription factors, later subdivision of the anterior-posterior and dorso-ventral axis of the neuroectoderm.

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