Diagnostic and Therapeutic Testis Biopsy

Overview

Journal Curr Urol Rep

Publisher Current Science

Specialty Urology

Date 2002 Jun 27

PMID 12084303

Citations 4

Authors

P T Chan

P N Schlegel

Affiliations

Soon will be listed here.

Abstract

Testicular biopsy has been traditionally used as a diagnostic tool in the management of infertility. With the advent of assisted reproductive technology, testicular biopsy is now used therapeutically to retrieve sperm for intracytoplasmic sperm injection (ICSI). The feasibility of testicular sperm extraction for ICSI is reviewed in this article. Although less invasive techniques such as testicular fine needle aspiration and percutaneous needle biopsy are efficacious, particularly in cases of obstructive azoospermia, studies in the current literature support that open testicular biopsy is a more reliable method to obtain testicular specimen. Different measures to reduce the complication rate of open testicular biopsy, including the application of microsurgical techniques, are addressed here. Other areas of recent development related to testicular biopsy that are reviewed include processing of testicular tissue, cryopreservation of retrieved spermatozoa, in vitro maturation of spermatozoa, and microinjection of immature spermatogenic precursor cells.

Citing Articles

Histopathological Pattern of Testicular Lesions in Kano, Northwestern Nigeria.

Abdulkadir A, Sanusi H, Alhaji S Niger J Surg. 2019; 25(2):158-162.

PMID: 31579369 PMC: 6771181. DOI: 10.4103/njs.NJS_44_18.

Pattern of testicular biopies as seen in a tertiary institution in nnewi, southeast Nigeria.

Oranusi C, Onyiaorah I, Ukah C Niger J Surg. 2014; 20(2):55-8.

PMID: 25191093 PMC: 4141445. DOI: 10.4103/1117-6806.137283.

Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropin.

Amory J, Coviello A, Page S, Anawalt B, Matsumoto A, Bremner W Fertil Steril. 2007; 89(2):380-6.

PMID: 17462643 PMC: 2674872. DOI: 10.1016/j.fertnstert.2007.02.059.

Isolation of ejaculated spermatozoa six hours after unsuccessful testicular biopsy in nonobstructive azoospermia.

Zadori J, Pal A, Kaali S J Assist Reprod Genet. 2003; 20(4):160-2.

PMID: 12762416 PMC: 3455633. DOI: 10.1023/a:1022985304771.

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