Determining the Extent of Cognitive Change After Coronary Surgery: a Review of Statistical Procedures

Overview

Journal Ann Thorac Surg

Publisher Elsevier

Specialties General Surgery
Pulmonary Medicine

Date 2002 Jun 25

PMID 12078822

Citations 26

Authors

Alexander Collie

David G Darby

Marina G Falleti

Brendan S Silbert

Paul Maruff

Affiliations

Soon will be listed here.

Abstract

Currently, cognitive decline after coronary surgery is said to be significant if the individual's postoperative test score is at least 1 standard deviation (SD) worse than their preoperative score. This "1-SD" technique fails to account for factors that may confound interpretation of serially acquired cognitive test scores, including regression to the mean, measurement error caused by poor test-retest reliability, and practice effects. We review the many alternative and potentially superior statistical techniques that have been described in the neuropsychologic and psychiatric literature for differentiating "true" changes in cognitive test score from changes caused by these factors.

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