Penicillin-binding Proteins 1a and 1b Form Independent Dimers in Escherichia Coli

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2002 Jun 12

PMID 12057973

Citations 12

Authors

Xavier Charpentier

Christian Chalut

Marie-Helene Remy

Jean-Michel Masson

Affiliations

Soon will be listed here.

Abstract

We report here that PBP1a can dimerize but does not interact with PBP1b to form PBP1a/PBP1b heterodimers in Escherichia coli. These findings support the idea of a relevant involvement of dimerization of both PBP1a and PBP1b during murein synthesis and suggest the existence of different peptidoglycan synthesis complexes.

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