Langerhans Cells in Actinic Reticuloid

Actinic reticuloid was observed in a patient following the development of porphyria cutanea tarda. A cutaneous lymphoma-like infiltrate was found histologically and at the ultrastructural level. In the infiltrate, the main population was histiocytic, with some mast cells and mononuclear cells. Most of the histiocytic cells contained numerous typical Langerhans granules and worm-like structures. Crystalloid cytoplasmic inclusions were occasionally detected.