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Male Germ Cell Specification and Differentiation

Overview
Journal Dev Cell
Publisher Cell Press
Date 2002 May 23
PMID 12015962
Citations 32
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Abstract

Understanding the mechanisms by which the germline is induced and maintained should lead to a broader understanding of the means by which pluripotency is acquired and maintained. In this review, two major aspects of male germ cell development are discussed: underlying mechanisms for induction and maintenance of primordial germ cells and the basic signaling pathways that determine spermatogonial cell fate.

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