The Effect of Cervical Vagotomy (decentralization) on the Ultrastructure of the Carotid Body on the Duck, Anas Platyrhynchos

Overview

Journal Cell Tissue Res

Specialties Anatomy & Histology
Cell Biology

Date 1975 Nov 19

PMID 1201590

Citations 4

Authors

P J Butler

M P Osborne

Affiliations

Soon will be listed here.

Abstract

Carotid bodies of ducks show no detectable changes in ultrastructure up to periods of four weeks following the removal of 2-3 cm of the cervical vagus (decentralization). This indicates that the majority, and possibily all the nerves terminating on the glomus cells are afferent (sensory) in nature. These nerve endings are in reciprocal synaptic contact with the glomus cells and therefore have efferent and afferent functions. Theories concerning the carotid body receptor mechanism are discussed with particular reference to those theories which ascribe functions to the reciprocal synapses.

Citing Articles

Comparative morphological and molecular studies on the oxygen-chemoreceptive cells in the carotid body and fish gills.

Kameda Y Cell Tissue Res. 2021; 384(2):255-273.

PMID: 33852077 DOI: 10.1007/s00441-021-03421-y.

Effects of distal vagal ganglionectomy and midcervical vagotomy on the ultrastructure of axonal elements in the carotid body of the domestic fowl.

Abdel-Magied E, King A J Anat. 1982; 134(Pt 4):643-52.

PMID: 7130032 PMC: 1167859.

The topographical anatomy and blood supply of the carotid body region of the domestic fowl.

Abdel-Magied E, King A J Anat. 1978; 126(Pt 3):535-46.

PMID: 689991 PMC: 1235669.

Carotid body chemoreceptor function: hypothesis based on a new circuit model.

Krammer E Proc Natl Acad Sci U S A. 1978; 75(5):2507-11.

PMID: 353814 PMC: 392583. DOI: 10.1073/pnas.75.5.2507.

References

Sampson S, BISCOE T . Efferent control of the carotid body chemoreceptor. Experientia. 1970; 26(3):261-2. DOI: 10.1007/BF01900082. View

Sampson S . Mechanism of efferent inhibition of carotid body chemoreceptors in the cat. Brain Res. 1972; 45(1):266-70. DOI: 10.1016/0006-8993(72)90236-3. View

Nishi K, STENSAAS L . The ultrastructure and source of nerve endings in the carotid body. Cell Tissue Res. 1974; 154(3):303-19. DOI: 10.1007/BF00223728. View

Metz B . Release of ACh from the carotid body by hypoxia and hypoxia plus hypercapnia. Respir Physiol. 1969; 6(3):386-94. DOI: 10.1016/0034-5687(69)90036-x. View

Goodman N . Efferent control of arterial chemoreceptors mediated by glossopharyngeal fibres and artifacts introduced by stimulation techniques. J Physiol. 1973; 230(2):295-311. PMC: 1350364. DOI: 10.1113/jphysiol.1973.sp010189. View

BOUVEROT P, Leitner L . Arterial chemoreceptors in the domestic fowl. Respir Physiol. 1972; 15(3):310-20. DOI: 10.1016/0034-5687(72)90072-2. View

Kobayashi S . Comparative cytological studies of the carotid body. 2. Ultrastructure of the synapses on the chief cell. Arch Histol Jpn. 1971; 33(5):397-420. DOI: 10.1679/aohc1950.33.397. View

BOUVEROT P, Hill N, Jammes Y . Ventilatory responses to CO2 in intact and chronically chemodenervated Peking ducks. Respir Physiol. 1974; 22(1-2):137-56. DOI: 10.1016/0034-5687(74)90053-x. View

Ishii K, Oosaki T . Fine structure of the chemoreceptor cell in the amphibian carotid labyrinth. J Anat. 1969; 104(Pt 2):263-80. PMC: 1232002. View

10.

Hess A, Zapata P . Innervation of the cat carotid body: normal and experimental studies. Fed Proc. 1972; 31(5):1365-82. View

11.

Kobayashi S, Uehara M . Occurrence of afferent synaptic complexes in the carotid body of the mouse. Arch Histol Jpn. 1970; 32(2):193-201. DOI: 10.1679/aohc1950.32.193. View

12.

Eyzaguirre C, Nishi K, Fidone S . Chemoreceptor synapses in the carotid body. Fed Proc. 1972; 31(5):1385-93. View

13.

BISCOE T, Sampson S . Stimulus response curves of single carotid body chemoreceptor afferent fibres. Nature. 1967; 215(5101):654-5. DOI: 10.1038/215654a0. View

14.

BISCOE T, Sampson S . Rhythmical and non-rhythmical spontaneous activity recorded from the central cut end of the sinus nerve. J Physiol. 1968; 196(2):327-38. PMC: 1351715. DOI: 10.1113/jphysiol.1968.sp008510. View

15.

Osborne M, Butlar P . New theory for receptor mechanism of carotid body chemoreceptors. Nature. 1975; 254(5502):701-3. DOI: 10.1038/254701a0. View

16.

ORegan R . Proceedings: Efferent inhibition of the chemoreceptor activity of the ischaemic carotid body. J Physiol. 1974; 239(2):95P-96P. View

17.

Zapata P . Effects of dopamine on carotid chemo- and baroreceptors in vitro. J Physiol. 1975; 244(1):235-51. PMC: 1330755. DOI: 10.1113/jphysiol.1975.sp010794. View

18.

Hellstrom S . Morphometric studies of dense-cored vesicles in type I cells of rat carotid body. J Neurocytol. 1975; 4(1):77-86. DOI: 10.1007/BF01099097. View

19.

Kondo H . An electron microscopic study on innervation of the carotid body of guinea pig. J Ultrastruct Res. 1971; 37(5):544-62. DOI: 10.1016/s0022-5320(71)80024-2. View

20.

BISCOE T, Stehbens W . Ultrastructure of the carotid body. J Cell Biol. 1966; 30(3):563-78. PMC: 2107013. DOI: 10.1083/jcb.30.3.563. View