Preliminary Studies on the Application of Enzyme Immunoassay in the Detection of Antibodies in Onchocerciasis

Overview

Journal Tropenmed Parasitol

Specialties Parasitology
Tropical Medicine

Date 1975 Sep 1

PMID 1189031

Citations 7

Authors

A Bartlett

D E BIDWELL

A Voller

Affiliations

Soon will be listed here.

Abstract

Preliminary enzyme-linked immunosorbent assay (ELISA) with serum from a patient with onchoceriasis revealed extensive cross-reactions with various nematode antigens. Further tests on a batch of sera from people with proven O. volvulus infections using O. gutturosa antigen, showed that almost all the sera gave higher ELISA values than did control African sera.

Citing Articles

Circulating immune complexes in onchocerciasis.

Paganelli R, Ngu J, Levinsky R Clin Exp Immunol. 1980; 39(3):570-5.

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Antibody determination in the diagnosis of Wuchereria bancrofti infection in man.

Dissanayake S, Ismail M Bull World Health Organ. 1981; 59(5):753-7.

PMID: 7032737 PMC: 2396112.

Immune complexes in Wuchereria bancrofti infection in man.

Dissanayake S, Galahitiyawa S, Ismail M Bull World Health Organ. 1982; 60(6):919-27.

PMID: 6761006 PMC: 2535970.

Isolation of antigen from Litomosoides carinii macrofilariae detecting serum antibodies due to Onchocerca volvulus.

Klenk A, GEYER E, Zahner H, Trojan H Z Parasitenkd. 1983; 69(3):377-86.

PMID: 6192603 DOI: 10.1007/BF00927879.

Immunological crossreactivity between a cloned antigen of Onchocerca volvulus and a component of the retinal pigment epithelium.

Braun G, McKechnie N, Connor V, Gilbert C, Engelbrecht F, Whitworth J J Exp Med. 1991; 174(1):169-77.

PMID: 2056276 PMC: 2118900. DOI: 10.1084/jem.174.1.169.