Experimental Trypanosoma Evansi Infection in South American Coati (Nasua Nasua): Hematological, Biochemical and Histopathological Changes

Overview

Journal Acta Trop

Publisher Elsevier

Specialty Tropical Medicine

Date 2002 Feb 12

PMID 11835897

Citations 9

Authors

H M Herrera

A C Alessi

L C Marques

A E Santana

L P C T Aquino

R F Menezes

M A V Moraes

R Z Machado

Affiliations

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Abstract

The course of an experimental Trypanosoma evansi infection in coatis (Nasua nasua, carnivora, Procyonidae) was followed for 262 days. Hematological analysis of the infected coatis revealed a marked decline in hemoglobin, packed-cell volume, and total erythrocyte count. An intense anemia followed the first wave of parasitemia and persisted until the end of the experimental period. Biochemical analysis showed increased serum levels of alanine aminotransferase and aspartate aminotransferase and decreased albumin. The main histopathological features consisted of myocarditis with the presence of degenerate cardiac fibers and meningoencephalitis. This study has shown that coatis infected with T. evansi develop a chronic disease.

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