Procalcitonin: How a Hormone Became a Marker and Mediator of Sepsis

Overview

Journal Swiss Med Wkly

Specialty General Medicine

Date 2002 Feb 1

PMID 11820070

Citations 42

Authors

B Muller

K L Becker

Affiliations

Soon will be listed here.

Abstract

Calcitonin was discovered in the early 1960s [1], at which time it was assumed to be a single hormone with a yet-to-be-determined role in human physiology. Since then it has been found to be only one entity among a large array of related circulating peptides, at least one of which has a pivotal role in the host response to microbial infections [2, 3]. The aim of this review is to describe this metamorphosis of an endocrine hormone to a new class of hormokine mediators in infectious diseases.

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