Effects of Glucagon and Insulin on the Paneth Cells of the Mouse Duodenum

Overview

Journal Experientia

Specialty Science

Date 1975 Sep 15

PMID 1175750

Citations 1

Authors

A Ahonen

A Penttila

Affiliations

Soon will be listed here.

Abstract

The effect of glucagon and insulin on the paneth cells (PC) of the duodenum of the mouse was investigated using light microscopy. Both glucagon and insulin were able to increase significantly the number of the secretory granules of PC. This possibly means that these hormones are capable of inhibiting the secretion of PC.

Citing Articles

The Paneth cell.

Sandow M, Whitehead R Gut. 1979; 20(5):420-31.

PMID: 381125 PMC: 1412432. DOI: 10.1136/gut.20.5.420.

References

BASSETT J . Plasma glucagon concentrations in sheep: their regulation and relation to concentrations of insulin and growth hormone. Aust J Biol Sci. 1972; 25(6):1277-87. DOI: 10.1071/bi9721277. View

LAUREN P, Sorvari T . Staining of Paneth cells with Best's carmine after methylation. Stain Technol. 1967; 42(6):311-5. DOI: 10.3109/10520296709115031. View

Ahonen A, Penttila . Effects of fasting and feeding and pilocarpine on paneth cells of the mouse. Scand J Gastroenterol. 1975; 10(4):347-52. View

HALLY A . The fine structure of the Paneth cell. J Anat. 1958; 92(2):268-77. PMC: 1249698. View

LINDSEY A, Santeusanio F, Braaten J, Faloona G, Unger R . Pancreatic alpha-cell function in trauma. JAMA. 1974; 227(7):757-61. View

Lin T, Evans D, Spray G . Mechanism studies of gastric inhibition by glucagon: failure of KCl and adrenergic blocking agents to prevent its action. Arch Int Pharmacodyn Ther. 1973; 202(2):314-24. View

KUROSUMI K . Electron microscopic analysis of the secretion mechanism. Int Rev Cytol. 1961; 11:1-124. DOI: 10.1016/s0074-7696(08)62713-8. View

Gerich J, KARAM J, FORSHAM P . Stimulation of glucagon secretion by epinephrine in man. J Clin Endocrinol Metab. 1973; 37(3):479-81. DOI: 10.1210/jcem-37-3-479. View

Ahonen A, Penttila A . Effect of Trasylol on Paneth cells of the mouse. Experientia. 1975; 31(5):577-8. DOI: 10.1007/BF01932467. View

10.

SELZMAN H, LIEBELT R . Paneth cell granule of mouse intestine. J Cell Biol. 1962; 15:136-9. PMC: 2106134. DOI: 10.1083/jcb.15.1.136. View

11.

Cherrington A, Vranic M, Fono P, Kovacevic N . Effect of glucagon on glucose turnover and plasma free fatty acids in depancreatized dogs maintained on matched insulin infusions. Can J Physiol Pharmacol. 1972; 50(10):946-54. DOI: 10.1139/y72-137. View

12.

Ahonen A . Histochemical and electron microscopic observations on the development, neural control and function of the Paneth cells of the mouse. Acta Physiol Scand Suppl. 1973; 398:1-71. View

13.

Lin T, Evans D, Spray G . Action of glucagon on electrolyte changes in the stomach, kidney and blood of dogs stimulated by pentagastrin or histamine. Arch Int Pharmacodyn Ther. 1973; 202(2):304-13. View

14.

Becker H, Reeder D, Thompson J . Effect of glucagon on circulating gastrin. Gastroenterology. 1973; 65(1):28-35. View

15.

MERCADIER M, Chigot J, CLOT J . [Is glucagon of value in the treatment of pancreatic diseases? Acute pancreatitis, fistulas]. Med Chir Dig. 1974; 3(2):101-4. View

16.

Kojima S, Ikeda M, Tsujimoto A . Effect of serotonin, glucagon and other hormones on amylase secretion from rabbit parotid gland. Jpn J Pharmacol. 1973; 23(4):588-91. DOI: 10.1254/jjp.23.588. View

17.

Weinstein I, Klausner H, Heimberg M . The effect of concentration of glucagon on output of triglyceride, ketone bodies, glucose, and urea by the liver. Biochim Biophys Acta. 1973; 296(2):300-9. DOI: 10.1016/0005-2760(73)90088-x. View