Topical Insecticide Treatments to Protect Dogs from Sand Fly Vectors of Leishmaniasis

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2001 Dec 19

PMID 11747701

Citations 11

Authors

R Reithinger

U Teodoro

C R Davies

Affiliations

Soon will be listed here.

Abstract

We compared the susceptibility of sand fly vectors to four topical insecticide treatments applied to domestic dogs, a reservoir of human leishmaniasis. Dogs were exposed to sand flies pretreatment and at 1 week, 1 month, and 2 months posttreatment. Sand fly bloodfeeding and survival rate of both fed and unfed flies were significantly reduced by the permethrin, deltamethrin, and fenthion treatments, but diazinon had no effect. The survival rate of bloodfed sand flies was reduced by up to 86% with deltamethrin collars. The antifeeding effect suggests that deltamethrin collars may be recommended to dog owners to protect their pets from sandfly- borne diseases. The combined effects on sand fly feeding and survival indicate that epidemiologic, community-based trials are warranted to test whether deltamethrin collars could reduce the incidence of canine and, hence, human leishmaniasis.

Citing Articles

Control of Canine Visceral Leishmaniasis: A Success Case Based on Deltamethrin 4% Collars.

de Camargo-Neves V, Calemes E, Rodas L, Galvis-Ovallos F, Silva L Epidemiologia (Basel). 2022; 2(4):502-518.

PMID: 36417213 PMC: 9620925. DOI: 10.3390/epidemiologia2040035.

A conceptual model for understanding the zoonotic cutaneous leishmaniasis transmission risk in the Moroccan pre-Saharan area.

Karmaoui A, Sereno D, Maia C, Campino L, El Jaafari S, Taybi A Parasite Epidemiol Control. 2022; 17:e00243.

PMID: 35243048 PMC: 8856991. DOI: 10.1016/j.parepi.2022.e00243.

Insecticide-impregnated dog collars reduce infantile clinical visceral leishmaniasis under operational conditions in NW Iran: A community-wide cluster randomised trial.

Courtenay O, Bazmani A, Parvizi P, Ready P, Cameron M PLoS Negl Trop Dis. 2019; 13(3):e0007193.

PMID: 30830929 PMC: 6417739. DOI: 10.1371/journal.pntd.0007193.

Effectiveness of deltamethrin-impregnated dog collars on the incidence of canine infection by Leishmania infantum: A large scale intervention study in an endemic area in Brazil.

Coura-Vital W, Leal G, Marques L, Pinheiro A, Carneiro M, Reis A PLoS One. 2018; 13(12):e0208613.

PMID: 30532255 PMC: 6287856. DOI: 10.1371/journal.pone.0208613.

A randomized, blinded, controlled trial to assess sand fly mortality of fluralaner administered orally in dogs.

Gomez S, Lucientes J, Castillo J, Peris M, Delacour S, Ortega P Parasit Vectors. 2018; 11(1):627.

PMID: 30518412 PMC: 6282346. DOI: 10.1186/s13071-018-3231-8.

References

Reithinger R, Davies C . Is the domestic dog (Canis familiaris) a reservoir host of American cutaneous leishmaniasis? A critical review of the current evidence. Am J Trop Med Hyg. 1999; 61(4):530-41. DOI: 10.4269/ajtmh.1999.61.530. View

Marsella R . Advances in flea control. Vet Clin North Am Small Anim Pract. 1999; 29(6):1407-24. DOI: 10.1016/s0195-5616(99)50135-6. View

Halbig P, Hodjati M, Mazloumi-Gavgani A, Mohite H, Davies C . Further evidence that deltamethrin-impregnated collars protect domestic dogs from sandfly bites. Med Vet Entomol. 2000; 14(2):223-6. DOI: 10.1046/j.1365-2915.2000.00229.x. View

Dereure J, Rioux J, Gallego M, Perieres J, Pratlong F, Mahjour J . Leishmania tropica in Morocco: infection in dogs. Trans R Soc Trop Med Hyg. 1991; 85(5):595. DOI: 10.1016/0035-9203(91)90356-4. View

Tesh R . Control of zoonotic visceral leishmaniasis: is it time to change strategies?. Am J Trop Med Hyg. 1995; 52(3):287-92. DOI: 10.4269/ajtmh.1995.52.287. View

Dye C . The logic of visceral leishmaniasis control. Am J Trop Med Hyg. 1996; 55(2):125-30. DOI: 10.4269/ajtmh.1996.55.125. View

Ashford R . Leishmaniasis reservoirs and their significance in control. Clin Dermatol. 1996; 14(5):523-32. DOI: 10.1016/0738-081x(96)00041-7. View

Arias J, Monteiro P, Zicker F . The reemergence of visceral leishmaniasis in Brazil. Emerg Infect Dis. 1996; 2(2):145-6. PMC: 2639817. DOI: 10.3201/eid0202.960213. View

Gothe R, Nolte I, KRAFT W . [Leishmaniasis in dogs in Germany: epidemiological case analysis and alternatives to conventional causal therapy]. Tierarztl Prax. 1997; 25(1):68-73. View

10.

Alvar J, Canavate C, Jimenez M, Laguna F, Lopez-Velez R, Molina R . Leishmania and human immunodeficiency virus coinfection: the first 10 years. Clin Microbiol Rev. 1997; 10(2):298-319. PMC: 172921. DOI: 10.1128/CMR.10.2.298. View

11.

Slappendel R, Teske E . The effect of intravenous or subcutaneous administration of meglumine antimonate (Glucantime) in dogs with leishmaniasis. A randomized clinical trial. Vet Q. 1997; 19(1):10-3. DOI: 10.1080/01652176.1997.9694729. View

12.

Killick-Kendrick R, Focheux C, Dereure J, Puech M, Cadiergues M . Protection of dogs from bites of phlebotomine sandflies by deltamethrin collars for control of canine leishmaniasis. Med Vet Entomol. 1997; 11(2):105-11. DOI: 10.1111/j.1365-2915.1997.tb00298.x. View

13.

Dietze R, Barros G, Teixeira L, Harris J, Michelson K, Falqueto A . Effect of eliminating seropositive canines on the transmission of visceral leishmaniasis in Brazil. Clin Infect Dis. 1997; 25(5):1240-2. DOI: 10.1086/516096. View

14.

Ashford D, David J, Freire M, David R, Sherlock I, Eulalio M . Studies on control of visceral leishmaniasis: impact of dog control on canine and human visceral leishmaniasis in Jacobina, Bahia, Brazil. Am J Trop Med Hyg. 1998; 59(1):53-7. DOI: 10.4269/ajtmh.1998.59.53. View

15.

Vieira J, Coelho G . [Visceral leishmaniasis or kala-azar: the epidemiological and control aspects]. Rev Soc Bras Med Trop. 1999; 31 Suppl 2:85-92. View

16.

Campbell-Lendrum D, Pinto M, De Souza A, Ready P, Davies C . Experimental comparison of anthropophily between geographically dispersed populations of Lutzomyia whitmani (Diptera: Psychodidae). Med Vet Entomol. 1999; 13(3):299-309. DOI: 10.1046/j.1365-2915.1999.00174.x. View