Comparing Cortical Activations for Silent and Overt Speech Using Event-related FMRI

Overview

Journal Hum Brain Mapp

Publisher Wiley

Specialty Neurology

Date 2001 Dec 18

PMID 11747099

Citations 79

Authors

Jie Huang

Thomas H Carr

Yue Cao

Affiliations

Soon will be listed here.

Abstract

At present, functional magnetic resonance imaging (fMRI) of cortical language functions favors "silent" task paradigms with no overt speaking, due to severe motion artifacts in MR images induced by vocalization. To the extent that the neural substrate of silent speaking might differ from that of overt speaking, this is a problem for understanding spoken language. The present study combined event related fMRI methodology with a set of techniques for motion reduction, detection, and correction to further investigate overt speech and compare it to silent speech. The purpose of the study was two-fold. We aimed to test a multiple-step image processing protocol involving discrimination and separation of motion-induced signals from activation-induced signals and we aimed to use this multi-step image processing protocol to compare the similarity of activation of cortical pathways potentially relevant to language production during silent and overt speech, focusing on Broca area and primary motor cortex as test cases. If the problem of motion artifact can be handled effectively, fMRI can add greatly to the tools available to investigate human language.

Citing Articles

Neural representations of the content and production of human vocalization.

Voigtlaender V, Sandhaeger F, Hawellek D, Hage S, Siegel M Proc Natl Acad Sci U S A. 2023; 120(23):e2219310120.

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[Key technology of brain-computer interaction based on speech imagery].

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Overt speech critically changes lateralization index and did not allow determination of hemispheric dominance for language: an fMRI study.

Berro D, Lemee J, Leiber L, Emery E, Menei P, Ter Minassian A BMC Neurosci. 2021; 22(1):74.

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