Observations on the Cause of Bowlegs in Achondroplasia
Overview
Affiliations
An analysis of 148 radiographs of the tibia during skeletal maturation in patients with achondroplasia was performed. The fibula was always longer than the tibia. The distance between the proximal tibial and fibular physis was less than normal throughout growth. The distance between the distal tibial and fibular physis was normal in childhood and became increasingly greater during growth. Tibia varus increased during growth, and there was a particular increase in distal tibia varus toward the end of growth. The altered growth characteristics of the bones suggest a formulation of cause of bowlegs in achondroplasia.
Hosl M, Thamm A, Afifi F, Nader S Children (Basel). 2025; 12(1).
PMID: 39857909 PMC: 11763588. DOI: 10.3390/children12010078.
Choi W, Shin J, Son S, Kim H, Hwang S, Park S Cartilage. 2024; :19476035241307862.
PMID: 39704117 PMC: 11660094. DOI: 10.1177/19476035241307862.
Nahm N, Mackenzie W, Mackenzie W, Gough E, Hashmi S, Hecht J Orphanet J Rare Dis. 2023; 18(1):139.
PMID: 37280669 PMC: 10246371. DOI: 10.1186/s13023-023-02738-x.
Improved distribution of leg forces after fibular resection and synostosis.
Rahman T, Oleas-Santillan G, Wee J, Mackenzie W J Exp Orthop. 2022; 9(1):43.
PMID: 35576083 PMC: 9110606. DOI: 10.1186/s40634-022-00480-0.
Drakou A, Koutsogewrgopoulou L, Boutzios G, Psifis M BMJ Case Rep. 2021; 14(9).
PMID: 34593545 PMC: 8487189. DOI: 10.1136/bcr-2021-242033.