Sequence and Expression Pattern of Ziro7, a Novel, Divergent Zebrafish Iroquois Homeobox Gene
Overview
Cell Biology
Reproductive Medicine
Affiliations
We have isolated the zebrafish ziro7 gene, a novel, divergent member of the Iroquois family. ziro7 is expressed at early epiboly stages in the dorsal half of the zebrafish embryo, with a higher level in the dorso-lateral margin. From mid-gastrulation stages onward, ziro7 is expressed in a large transversal stripe in the future neural plate, which subsequently divides into thinner stripes located in the diencephalon, midbrain and hindbrain.
Pineal progenitors originate from a non-neural territory limited by FGF signalling.
Staudt N, Giger F, Fielding T, Hutt J, Foucher I, Snowden V Development. 2019; 146(22).
PMID: 31754007 PMC: 7375831. DOI: 10.1242/dev.171405.
Maeso I, Irimia M, Tena J, Gonzalez-Perez E, Tran D, Ravi V Genome Res. 2012; 22(4):642-55.
PMID: 22234889 PMC: 3317147. DOI: 10.1101/gr.132233.111.
The prethalamus is established during gastrulation and influences diencephalic regionalization.
Staudt N, Houart C PLoS Biol. 2007; 5(4):e69.
PMID: 17341136 PMC: 1808486. DOI: 10.1371/journal.pbio.0050069.
Organization of Iroquois genes in fish.
Dildrop R, Ruther U Dev Genes Evol. 2004; 214(6):267-76.
PMID: 15133664 DOI: 10.1007/s00427-004-0402-8.
Feijoo C, Manzanares M, de la Calle-Mustienes E, Gomez-Skarmeta J, Allende M Dev Genes Evol. 2004; 214(6):277-84.
PMID: 15064948 DOI: 10.1007/s00427-004-0401-9.