Genome Structure of Ebola Virus Subtype Reston: Differences Among Ebola Subtypes. Brief Report

Overview

Journal Arch Virol

Specialty Microbiology

Date 2001 Nov 28

PMID 11722021

Citations 17

Authors

T Ikegami

A B Calaor

M E Miranda

M Niikura

M Saijo

I Kurane

Y Yoshikawa

S Morikawa

Affiliations

Soon will be listed here.

Abstract

We determined the complete genome sequence of Ebola virus subtype Reston (EBO-R) in the Philippines in 1996. The deduced transcriptional signals were highly conserved among Ebola viruses except for the stop signal of L genes. The intergenic regions were composed of 4 to 7 nucleotides, and of 2 characteristic overlaps and a long intergenic region. The glycoprotein (GP) had several amino acid differences from EBO-R isolated in 1989 and 1992. The variety of GP sequences strongly suggests the independent introduction of EBO-R from unknown natural reservoirs in 1996.

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