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Opsoclonus: Its Clinical Value

Overview
Journal Neurology
Specialty Neurology
Date 1975 Jun 1
PMID 1168869
Citations 9
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Abstract

Although the exact site of pathologic involvement and the pathogenesis remain uncertain, opsoclonus is an invaluable clinical sign that in it alone may herald an occult systemic malignancy. A thorough systematic evaluation should be undertaken to exclude an occult neoplasm in any patient who presents with opsoclonus unaccompanied by any other clinical sign.

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A review of the therapy of paraneoplastic neurologic syndromes.

Das A, Hochberg F, McNelis S J Neurooncol. 1999; 41(2):181-94.

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Cerebellar ataxia and opsoclonus as the initial manifestations of myoclonic encephalopathy associated with neuroblastoma.

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