» Articles » PMID: 1159781

Comparison of Some Permeability Properties of Rat Liver Slices, Liver Cells in Suspension, and in Vivo-produced Aggregates of Dispersed Liver Cells

Overview
Journal J Membr Biol
Date 1975 Jul 24
PMID 1159781
Citations 3
Authors
Affiliations
Soon will be listed here.
Abstract

It has been reported earlier that when rat liver is dispersed to a single cell suspension, the parenchymal cells lose the ability to take up pyrimidine bases but acquire the ability to take up RNAase and macromolecular nucleic acids. It is now shown that these changes are largely reversed on intraperitoneal reaggregation of the parenchymal cells and that, in these respects, the aggregates behave more like the organized tissue than like the dispersed cells.

Citing Articles

A comparison of the ability of normal liver, a premalignant liver, a solid hepatoma and the Zajdela ascitic hepatoma, to take up amino acids in vitro.

Bhargava P, SZAFARZ D, Bornecque C, ZAJDELA F J Membr Biol. 1976; 26(1):31-41.

PMID: 1255703 DOI: 10.1007/BF01868864.


Effect of cell concentration on the uptake of amino acids by rat liver parenchymal cells in suspension.

Bhargava P, Siddiqui M, Kumar G, Prasad K J Membr Biol. 1975; 22(3-4):357-68.

PMID: 1159782 DOI: 10.1007/BF01868180.


Uptake in vitro of nucleic acid precursors and nucleic acids by Zajdela ascitic hepatoma cells.

Bhargava P, SZAFARZ D, Bornecque C, ZAJDELA F J Membr Biol. 1975; 22(3-4):341-56.

PMID: 169353 DOI: 10.1007/BF01868179.

References
1.
LAWS J, Stickland L . The adhesion of liver cells. Exp Cell Res. 1961; 24:240-54. DOI: 10.1016/0014-4827(61)90426-8. View

2.
Jacob S, Bhargava P . METABOLISM OF TISSUE CELLS IN SUSPENSION. SYNTHESIS OF RIBONUCLEIC ACID BY LEIVER CELLS IN SUSPENSION. Biochem J. 1965; 95:568-76. PMC: 1214358. DOI: 10.1042/bj0950568. View

3.
Bhargava P, Shanmugam G . Uptake of nonviral nucleic acids by mammalian cells. Prog Nucleic Acid Res Mol Biol. 1971; 11:103-92. DOI: 10.1016/s0079-6603(08)60327-x. View

4.
Barnard P, WEISS L, Ratcliffe T . Changes in the surface properties of embryonic chick neural retina cells after dissociation. Exp Cell Res. 1969; 54(3):293-301. DOI: 10.1016/0014-4827(69)90205-5. View

5.
Kumar B, Bhargava P . The effect of ribonuclease on rat-liver parenchymal cells in suspension. Biochimie. 1973; 55(6):661-70. DOI: 10.1016/s0300-9084(73)80019-7. View