Assessment of Subclinical Atherosclerosis and Cardiovascular Risk

Overview

Journal Clin Cardiol

Specialty Cardiology & Vascular Diseases

Date 2001 Oct 12

PMID 11594409

Citations 3

Authors

R M Benitez

R A Vogel

Affiliations

Soon will be listed here.

Abstract

Conventional cardiac risk factors do not fully explain the incidence of coronary artery disease and coronary events. Risk stratification and therapy based solely on these conventional risk factors may exclude a population who would otherwise benefit from lifestyle and risk factor modification. Recent efforts to improve our ability to recognize individuals and populations at increased risk of coronary events have focused on the noninvasive imaging of atherosclerosis, both in coronary and extracoronary arterial beds, or the identification of "non-traditional" serum markers. We review the complimentary role of these newer methods of risk stratification in the context of conventional risk factor evaluation.

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References

Kol A, Bourcier T, Lichtman A, Libby P . Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages. J Clin Invest. 1999; 103(4):571-7. PMC: 408102. DOI: 10.1172/JCI5310. View

Jodoin I, Bussieres L, Tardif J, Juneau M . Effect of a short-term primary prevention program on endothelium-dependent vasodilation in adults at risk for atherosclerosis. Can J Cardiol. 1999; 15(1):83-8. View

Wu K, Aleksic N . Platelet glycoprotein polymorphism and risk for coronary heart disease. Blood Coagul Fibrinolysis. 1999; 10 Suppl 1:S63-5. View

Yataco A, Corretti M, Gardner A, Womack C, Katzel L . Endothelial reactivity and cardiac risk factors in older patients with peripheral arterial disease. Am J Cardiol. 1999; 83(5):754-8. DOI: 10.1016/s0002-9149(98)00984-9. View

Anderson J, Muhlestein J, Carlquist J, Allen A, Trehan S, Nielson C . Randomized secondary prevention trial of azithromycin in patients with coronary artery disease and serological evidence for Chlamydia pneumoniae infection: The Azithromycin in Coronary Artery Disease: Elimination of Myocardial Infection with.... Circulation. 1999; 99(12):1540-7. DOI: 10.1161/01.cir.99.12.1540. View

Gurfinkel E, Bozovich G, Beck E, Testa E, Livellara B, MAUTNER B . Treatment with the antibiotic roxithromycin in patients with acute non-Q-wave coronary syndromes. The final report of the ROXIS Study. Eur Heart J. 1999; 20(2):121-7. DOI: 10.1053/euhj.1998.1283. View

Clarkson P, Montgomery H, Mullen M, Donald A, Powe A, Bull T . Exercise training enhances endothelial function in young men. J Am Coll Cardiol. 1999; 33(5):1379-85. DOI: 10.1016/s0735-1097(99)00036-4. View

Duerinckx A . Coronary MR angiography. Radiol Clin North Am. 1999; 37(2):273-318, v. DOI: 10.1016/s0033-8389(05)70096-8. View

Krull M, Klucken A, Wuppermann F, Fuhrmann O, Magerl C, Seybold J . Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae. J Immunol. 1999; 162(8):4834-41. View

10.

Kessler W, Laub G, Achenbach S, Ropers D, Moshage W, Daniel W . Coronary arteries: MR angiography with fast contrast-enhanced three-dimensional breath-hold imaging--initial experience. Radiology. 1999; 210(2):566-72. DOI: 10.1148/radiology.210.2.r99fe38566. View

11.

de Maat M, Bladbjerg E, Johansen L, de Knijff P, Gram J, Kluft C . DNA-polymorphisms and plasma levels of vascular disease risk factors in Greenland Inuit--is there a relation with the low risk of cardiovascular disease in the Inuit?. Thromb Haemost. 1999; 81(4):547-52. View

12.

Detrano R, Wong N, Doherty T, Shavelle R, Tang W, Ginzton L . Coronary calcium does not accurately predict near-term future coronary events in high-risk adults. Circulation. 1999; 99(20):2633-8. DOI: 10.1161/01.cir.99.20.2633. View

13.

Coombes B, Mahony J . Chlamydia pneumoniae infection of human endothelial cells induces proliferation of smooth muscle cells via an endothelial cell-derived soluble factor(s). Infect Immun. 1999; 67(6):2909-15. PMC: 96599. DOI: 10.1128/IAI.67.6.2909-2915.1999. View

14.

Salomaa V, Matei C, Aleksic N, Sansores-Garcia L, Folsom A, Juneja H . Soluble thrombomodulin as a predictor of incident coronary heart disease and symptomless carotid artery atherosclerosis in the Atherosclerosis Risk in Communities (ARIC) Study: a case-cohort study. Lancet. 1999; 353(9166):1729-34. DOI: 10.1016/s0140-6736(98)09057-6. View

15.

Danesh J, Muir J, Wong Y, Ward M, Gallimore J, Pepys M . Risk factors for coronary heart disease and acute-phase proteins. A population-based study. Eur Heart J. 1999; 20(13):954-9. DOI: 10.1053/euhj.1998.1309. View

16.

Taylor A, Keegan J, Jhooti P, Gatehouse P, Firmin D, Pennell D . Differences between normal subjects and patients with coronary artery disease for three different MR coronary angiography respiratory suppression techniques. J Magn Reson Imaging. 1999; 9(6):786-93. DOI: 10.1002/(sici)1522-2586(199906)9:6<786::aid-jmri5>3.0.co;2-t. View

17.

Sakuma H, Takeda K, Higgins C . Fast magnetic resonance imaging of the heart. Eur J Radiol. 1999; 29(2):101-13. DOI: 10.1016/s0720-048x(98)00173-9. View

18.

Dupuis J, Tardif J, Cernacek P, Theroux P . Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial. Circulation. 1999; 99(25):3227-33. DOI: 10.1161/01.cir.99.25.3227. View

19.

Hundley W, Hamilton C, Clarke G, Hillis L, Herrington D, Lange R . Visualization and functional assessment of proximal and middle left anterior descending coronary stenoses in humans with magnetic resonance imaging. Circulation. 1999; 99(25):3248-54. DOI: 10.1161/01.cir.99.25.3248. View

20.

Ridker P, Rifai N, Pfeffer M, Sacks F, Braunwald E . Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators. Circulation. 1999; 100(3):230-5. DOI: 10.1161/01.cir.100.3.230. View