To Cleave or Not to Cleave? Insights from the LexA Crystal Structure

Overview

Journal Mol Cell

Publisher Cell Press

Specialty Cell Biology

Date 2001 Oct 5

PMID 11583611

Citations 3

Authors

G C Walker

Affiliations

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Abstract

In the September 7, 2001 issue of Cell, Luo et al. describe the structure of LexA protein in two states, cleavable and noncleavable. This structure offers new insights into how LexA and other structurally related proteins, such as lambda and UmuD, undergo autocatalytic cleavage using a Ser-Lys dyad.

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