Body Mass Index As a Predictor of Continued Survival in Older Chronic Dialysis Patients

Overview

Journal Int Urol Nephrol

Publisher Springer

Specialty Nephrology

Date 2001 Oct 5

PMID 11583369

Citations 10

Authors

N G Kutner

R Zhang

Affiliations

Soon will be listed here.

Abstract

Objective: To investigate the contribution of body mass index (BMI) to mortality over 11 years of follow-up in a prevalent sample of dialysis patients aged 60+.

Design: Multivariate Cox proportional hazards regression analysis.

Setting: Multicenter stratified random sample of black and white older chronic dialysis patients in a southeastern state.

Subjects: 316 patients on hemodialysis (HD) and peritoneal dialysis (PD).

Main Outcome Measure: Continued survival from baseline interview in 1988 to June 1999.

Results: Adjusting for age, primary diagnosis of diabetes, cardiovascular comorbidity, HD/PD therapy, and patient-reported functional impairment, the interaction of baseline BMI with race and gender was associated with older patients' risk of mortality. Black females, black males, and white males with higher BMI had a reduced risk of mortality, while no protective effect of higher BMI was found for white females. Patients with cardiovascular comorbidity and greater functional impairment at baseline had increased mortality risk. BMI was not significantly correlated with serum albumin or functional impairment.

Conclusion: BMI, a simple anthropometric measure that provides a marker of nutritional status, interacts with race and gender to predict long-term survival in older dialysis patients. The association of survival with dialysis adequacy, nutritional indicators, and cardiovascular status in black and white dialysis patients is an important area of study.

Citing Articles

Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis.

Song Y, Cai G, Xiao Y, Chen X BMC Nephrol. 2020; 21(1):377.

PMID: 32867718 PMC: 7457491. DOI: 10.1186/s12882-020-02026-x.

Lower body mass index and mortality in older adults starting dialysis.

Polinder-Bos H, van Diepen M, Dekker F, Hoogeveen E, Franssen C, Gansevoort R Sci Rep. 2018; 8(1):12858.

PMID: 30150623 PMC: 6110755. DOI: 10.1038/s41598-018-30952-2.

Advanced wasting in peritoneal dialysis patients.

Xu Z, Murata G, Glew R, Sun Y, Vigil D, Servilla K World J Nephrol. 2017; 6(3):143-149.

PMID: 28540204 PMC: 5424436. DOI: 10.5527/wjn.v6.i3.143.

Residual urinary output in high body mass index individuals on chronic hemodialysis: A disregarded life vest?.

Trimarchi H, Rana M, Karl A, Andrews J, Dicugno M, Pomeranz V World J Nephrol. 2014; 3(4):317-23.

PMID: 25374828 PMC: 4220367. DOI: 10.5527/wjn.v3.i4.317.

Effect of age and dialysis vintage on obesity paradox in long-term hemodialysis patients.

Vashistha T, Mehrotra R, Park J, Streja E, Dukkipati R, Nissenson A Am J Kidney Dis. 2013; 63(4):612-22.

PMID: 24120224 PMC: 3969454. DOI: 10.1053/j.ajkd.2013.07.021.

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