Zhang L, Xu P, Yan X
ACS Pharmacol Transl Sci. 2025; 8(1):189-202.
PMID: 39816799
PMC: 11729431.
DOI: 10.1021/acsptsci.4c00575.
Kim S, Mugundu G, Singh A
Clin Transl Sci. 2024; 17(12):e70101.
PMID: 39696762
PMC: 11655386.
DOI: 10.1111/cts.70101.
Lu S, Corpstein C, Park K, Li T
ADMET DMPK. 2024; 12(5):705-719.
PMID: 39524219
PMC: 11542719.
DOI: 10.5599/admet.2415.
Chen C, Zhou X, Lavezzi S, Arshad U, Sharma R
J Transl Med. 2023; 21(1):17.
PMID: 36631827
PMC: 9832631.
DOI: 10.1186/s12967-022-03849-y.
Ma C, Almasan A, Gurkan-Cavusoglu E
PLoS Comput Biol. 2022; 18(11):e1010685.
PMID: 36395103
PMC: 9671373.
DOI: 10.1371/journal.pcbi.1010685.
Network-Based Systems Analysis Explains Sequence-Dependent Synergism of Bortezomib and Vorinostat in Multiple Myeloma.
Nanavati C, Mager D
AAPS J. 2021; 23(5):101.
PMID: 34403034
DOI: 10.1208/s12248-021-00622-9.
Multiscale and Translational Quantitative Systems Toxicology, Pharmacokinetic-Toxicodynamic Modeling Analysis for Assessment of Doxorubicin-Induced Cardiotoxicity.
Vaidya T, Mody H, Franco Y, Brown A, Ait-Oudhia S
AAPS J. 2021; 23(1):18.
PMID: 33404976
DOI: 10.1208/s12248-020-00542-0.
A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer.
Franco Y, Ramakrishnan V, Vaidya T, Mody H, Perez L, Ait-Oudhia S
J Pharmacokinet Pharmacodyn. 2021; 48(2):273-293.
PMID: 33389550
DOI: 10.1007/s10928-020-09732-x.
Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges.
Zou H, Banerjee P, Leung S, Yan X
Front Pharmacol. 2020; 11:997.
PMID: 32719604
PMC: 7348046.
DOI: 10.3389/fphar.2020.00997.
Transitioning from Basic toward Systems Pharmacodynamic Models: Lessons from Corticosteroids.
Ayyar V, Jusko W
Pharmacol Rev. 2020; 72(2):414-438.
PMID: 32123034
PMC: 7058984.
DOI: 10.1124/pr.119.018101.
Semi-Mechanism-Based Pharmacokinetic-Toxicodynamic Model of Oxaliplatin-Induced Acute and Chronic Neuropathy.
Kobuchi S, Shimizu R, Ito A
Pharmaceutics. 2020; 12(2).
PMID: 32028733
PMC: 7076355.
DOI: 10.3390/pharmaceutics12020125.
Pharmacokinetic and Pharmacodynamic Properties of Drug Delivery Systems.
Glassman P, Muzykantov V
J Pharmacol Exp Ther. 2019; 370(3):570-580.
PMID: 30837281
PMC: 6806371.
DOI: 10.1124/jpet.119.257113.
Pharmacodynamic Models of Differential Bortezomib Signaling Across Several Cell Lines of Multiple Myeloma.
Ramakrishnan V, Mager D
CPT Pharmacometrics Syst Pharmacol. 2018; 8(3):146-157.
PMID: 30516019
PMC: 6430155.
DOI: 10.1002/psp4.12358.
Utility of a Novel Three-Dimensional and Dynamic (3DD) Cell Culture System for PK/PD Studies: Evaluation of a Triple Combination Therapy at Overcoming Anti-HER2 Treatment Resistance in Breast Cancer.
Ande A, Vaidya T, Tran B, Vicchiarelli M, Brown A, Ait-Oudhia S
Front Pharmacol. 2018; 9:403.
PMID: 29765318
PMC: 5938355.
DOI: 10.3389/fphar.2018.00403.
Systems pharmacological analysis of mitochondrial cardiotoxicity induced by selected tyrosine kinase inhibitors.
Vaidya T, Kamta J, Chaar M, Ande A, Ait-Oudhia S
J Pharmacokinet Pharmacodyn. 2018; 45(3):401-418.
PMID: 29446053
DOI: 10.1007/s10928-018-9578-9.
Cell Signaling Model Connects Vorinostat Pharmacokinetics and Tumor Growth Response in Multiple Myeloma Xenografts.
Nanavati C, Ruszaj D, Mager D
CPT Pharmacometrics Syst Pharmacol. 2017; 6(11):756-764.
PMID: 29045072
PMC: 5702904.
DOI: 10.1002/psp4.12246.
Pharmacokinetics and Pharmacodynamics of the Triterpenoid Ursolic Acid in Regulating the Antioxidant, Anti-inflammatory, and Epigenetic Gene Responses in Rat Leukocytes.
Zhang C, Wang C, Li W, Wu R, Guo Y, Cheng D
Mol Pharm. 2017; 14(11):3709-3717.
PMID: 29035547
PMC: 5697757.
DOI: 10.1021/acs.molpharmaceut.7b00469.
Array of translational systems pharmacodynamic models of anti-cancer drugs.
Ait-Oudhia S, Mager D
J Pharmacokinet Pharmacodyn. 2016; 43(6):549-565.
PMID: 27771815
DOI: 10.1007/s10928-016-9497-6.
Systems pharmacology and enhanced pharmacodynamic models for understanding antibody-based drug action and toxicity.
Ait-Oudhia S, Ovacik M, Mager D
MAbs. 2016; 9(1):15-28.
PMID: 27661132
PMC: 5240652.
DOI: 10.1080/19420862.2016.1238995.
Pharmacokinetic-pharmacodynamic modeling of the antitumor effect of TM208 and EGFR-TKI resistance in human breast cancer xenograft mice.
Ji X, Ji S, Li R, Wu K, Zhu X, Lu W
Acta Pharmacol Sin. 2016; 37(6):825-33.
PMID: 27133303
PMC: 4954772.
DOI: 10.1038/aps.2016.40.