» Articles » PMID: 11534758

HIV-1 Integrase Inhibitory Phenylpropanoid Glycosides from Clerodendron Trichotomum

Overview
Journal Arch Pharm Res
Specialty Pharmacology
Date 2001 Sep 6
PMID 11534758
Citations 10
Authors
Affiliations
Soon will be listed here.
Abstract

Seven phenylpropanoid glycosides named acteoside (1), acteoside isomer (2), leucosceptoside A (3), plantainoside C (4), jionoside D (5), martynoside (6), and isomartynoside (7) were isolated from Clerodendron trichotomum. Compounds 1 and 2 showed potent inhibitory activities against HIV-1 integrase with IC50 values of 7.8 +/- 3.6 and 13.7 +/- 6.0 microM, respectively.

Citing Articles

Thunb.: a review on phytochemical composition and pharmacological activities.

Li L, Tang Z, Xiao S, Dai X, Wang Y, Wei X Front Pharmacol. 2025; 15():1505851.

PMID: 39834825 PMC: 11743446. DOI: 10.3389/fphar.2024.1505851.


Thunberg-An Ornamental Shrub with Medical Properties.

Gomulski J, Grzegorczyk-Karolak I Molecules. 2024; 29(14).

PMID: 39064848 PMC: 11279216. DOI: 10.3390/molecules29143272.


Green Synthesis of Aluminum Oxide Nanoparticles Using Clerodendrum phlomidis and Their Antibacterial, Anti-inflammatory, and Antioxidant Activities.

Thanaraj S, Mitthun A, Geetha Sravanthy P, Carmelin D, Surya M, Saravanan M Cureus. 2024; 16(1):e52279.

PMID: 38357054 PMC: 10864816. DOI: 10.7759/cureus.52279.


Bioassay Analysis and Molecular Docking Study Revealed the Potential Medicinal Activities of Active Compounds Polygonumins B, C and D from ().

Ahmad R, Rosandy A, Sahidin I, Ab Ghani N, Noor N, Baharum S Plants (Basel). 2023; 12(1).

PMID: 36616187 PMC: 9823858. DOI: 10.3390/plants12010059.


Leucosceptosides A and B: Two Phenyl-Ethanoid Glycosides with Important Occurrence and Biological Activities.

Frezza C, De Vita D, Toniolo C, Sciubba F, Tomassini L, Venditti A Biomolecules. 2022; 12(12).

PMID: 36551235 PMC: 9775335. DOI: 10.3390/biom12121807.